Evidence map›Paper›PMID 26130940›Full record

ArticlePharmacognosy research

Are herbal mouthwash efficacious over chlorhexidine on the dental plaque?

Devanand Gupta, Swapna Nayan, Harshad K Tippanawar, Gaurav I Patil, Ankita Jain, Rizwan K Momin, Rajendra Kumar Gupta

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Pharmacognosy research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03773094 (Effect of Guava Leaves Extract Mouth Wash on Antibacterial Activity, Salivary pH and Patient Satisfaction Compared to Chlorhexidine Mouth Wash in High Caries Risk Patients), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03773094 phase2 / phase3unknown statusnot on this map

Effect of Guava Leaves Extract Mouth Wash on Antibacterial Activity, Salivary pH and Patient Satisfaction Compared to Chlorhexidine Mouth Wash in High Caries Risk Patients: A Randomized Control Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2019 to 2020Enrolled94ConditionsHigh Caries Risk Patients, Antimicrobial Effect, Salivary pH, Patient Satisfaction to TasteArmsGuava leaves extract, Chlorhexidine
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Assessment of the Efficacy ofInternational journal of clinical pediatric dentistry · 2025
    Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Devanand GuptaDepartment of Public Health Dentistry, Institute of Dental Science, Bareilly, Uttar Pradesh, India ; General Secretary, International Society for Holistic Dentistry, Uttrakhand, India.
Swapna NayanDepartment of Oral and Maxillofacial Surgery, D.Y Patil Dental College, Nerul, Navi Mumbai, Maharashtra, India.
Harshad K TippanawarDepartment of Conservative, Endodontics and Esthetics Dentistry, JSS Dental College and Hospital, Mysore, India.
Gaurav I PatilDepartment of Orthodontics and Dentofacial Orthopaedics, JSS Dental College and Hospital, Mysore, India.
Ankita JainDepartment of Public Health Dentistry, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, India.
Rizwan K MominDepartment of Oral Pathology, Jaipur Dental College, Jaipur, India.
Rajendra Kumar GuptaPrincipal, Government Degree college, Banbasa, Uttrakhand, India.
JSS Dental College and Hospital · INRajasthan Dental College and Hospital · INTeerthanker Mahaveer University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare the effect of herbal extract mouthwash and chlorhexidine mouthwash on the dental plaque level. MATERIALS AND

methodsThe subjects (60 healthy medical students aged ranges between 20 and 25 years) were randomly divided into two groups, that is, the herbal group and the chlorhexidine gluconate mouthwash group. The data were collected at the baseline and 3 days. The plaque was disclosed using erythrosine disclosing agent and their scores were recorded using the Quigley and Hein plaque index modified by Turesky-Gilmore-Glickman. Statistical analysis was carried out later to compare the effect of all the two groups.

resultsOur result showed that the chlorhexidine group shows a greater decrease in plaque score followed by herbal extract, but the result was statistically insignificant.

conclusionThe results indicate that herbal mouthwash may prove to be an effective agent owing to its ability to reduce plaque level, especially in low socioeconomic strata.

Indexed as

Chlorhexidineherbal mouthwashholistic dentistryplaque index

Identifiers

PMID26130940
PMCPMC4471655
OpenAlexW1973238434

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.