ReviewPharmacognosy research
Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds.
Review in Pharmacognosy research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04249869 (The Effect of Traditional Chinese Medicine), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Traditional Chinese Medicine (VGH-AD1) on Patients With Alzheimer's Disease: A Double-blinded Randomized Placebo-controlled Cross-over Study
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Potential Hepatotoxins Found in Herbal Medicinal Products: A Systematic Review.International journal of molecular sciences · 2020Pooled it
- Impact of 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucoside on cognitive deficits in animal models of Alzheimer's disease: a systematic review.BMC complementary and alternative medicine · 2016Pooled it
- Integrative chloroplast genomics of Polygonaceae: evolutionary dynamics, codon optimization, and phylogenetic resolution.BMC plant biology · 2026Article
- Bioinspired engineering ofFrontiers in physiology · 2026Article
- Elucidating the Mechanism of Emodin in Treating Post-Stroke Depression Through Network Pharmacology and Animal Experiments.CNS neuroscience & therapeutics · 2025Article
- [Comparison of clinical characteristics between patients with Polygonum multiflorum-induced liver injury and those with other drug-induced liver injuries].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Article
- Processing-induced reduction in dianthrones content and toxicity of Polygonum multiflorum: Insights from ultra-high performance liquid chromatography triple quadrupole mass spectrometry analysis and toxicological assessment.Animal models and experimental medicine · 2025Article
- A Randomized, Placebo-controlled Clinical Study Evaluating a Dietary Supplement for Hair Growth.The Journal of clinical and aesthetic dermatology · 2024Article
- Efficacy of Heshouwu () on gut mircobiota in mice with autoimmune encephalomyelitis.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023Article
- Article
- Assessing potential liver injury induced byPharmaceutical biology · 2022Article
- Exploratory Quality Control Study forMolecules (Basel, Switzerland) · 2022Article
- A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2022Review
- Editorial: Application of plant secondary metabolites to pain neuromodulation, volume II.Frontiers in pharmacology · 2022Article
- A first approach for the micropropagation of the medicinal halophyteFrontiers in plant science · 2022Article
- Medicinal Plants with Potential Inhibitory Bioactive Compounds against Coronaviruses.Advanced pharmaceutical bulletin · 2022Review
- Global Perspective of Plant-Based Cosmetic Industry and Possible Contribution of Sri Lanka to the Development of Herbal Cosmetics.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Modulation of Hair Growth Promoting Effect by Natural Products.Pharmaceutics · 2021Review
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for the treatment of various diseases and medical conditions such as liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. International databases such as PubMed/Medline, Science citation Index and Google Scholar were searched for clinical studies recently published on P. multiflorum. Various clinical studies published articles were retrieved, providing information relevant to pharmacokinetics-pharmacodynamics analysis, sleep disorders, dyslipidemia treatment, and neurodegenerative diseases. This review is an effort to update the clinical picture of investigations ever carried on PMT and/or its isolated bio-compounds and to enlighten its therapeutic assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.