Observational studyObesity surgery2016
The Effect of Ventilation Strategy on Arterial and Cerebral Oxygenation During Laparoscopic Bariatric Surgery.
Observational study in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Effect of the Prolonged Inspiratory to Expiratory Ratio on Oxygenation and Respiratory Mechanics During Surgical Procedures.Medicine · 2016Pooled it
- Effects of ventilatory strategy on arterial oxygenation and respiratory mechanics in overweight and obese patients undergoing posterior spine surgery.Scientific reports · 2019Trial
- Effect of prolonged inspiratory time on gas exchange during robot-assisted laparoscopic urologic surgery.Der Anaesthesist · 2018Trial
- The effect of pressure-controlled inverse ratio ventilation on lung protection in obese patients undergoing gynecological laparoscopic surgery.Journal of anesthesia · 2017Trial
- Volume-controlled inverse ratio ventilation improves safe apnea time in obese patients during the induction of general anesthesia: a randomized controlled trial.Frontiers in medicine · 2025Article
- The Impact of Pneumoperitoneum on Mean Expiratory Flow Rate: Observational Insights from Patients with Healthy Lungs.Diagnostics (Basel, Switzerland) · 2024Article
- What is the proper ventilation strategy during laparoscopic surgery?Korean journal of anesthesiology · 2017Review
- The Effect of Ventilation Strategy on Arterial and Cerebral Oxygenation During Laparoscopic Bariatric Surgery.Obesity surgery · 2017Article
- Effect of general anesthesia on serum β-amyloid protein and regional cerebral oxygen saturation of elderly patients after subtotal gastrectomy.Experimental and therapeutic medicine · 2016Article
- Letter to the Editor: The Effect of Ventilation Strategy on Arterial and Cerebral Oxygenation During Laparoscopic Bariatric Surgery.Obesity surgery · 2016Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe investigated the effect of prolonged inspiratory to expiratory (I/E) ratio ventilation on respiratory mechanics, gas exchange, and regional cerebral oxygen saturation (rSO2) in obese patients undergoing laparoscopic bariatric surgery in the reverse Trendelenburg position.
methodsTwenty-eight adult patients scheduled for laparoscopic sleeve gastrectomy were enrolled in this prospective observational study. After anesthesia induction, pressure-controlled ventilation was conducted initially at a conventional I/E ratio of 1:2 and a positive end-expiratory pressure of 5 cmH2O. Twenty minutes after pneumoperitoneum, the I/E ratio was changed to 1:1 for 20 min and then to 2:1 for 20 min. Hemodynamic variables, end-tidal carbon dioxide tension, rSO2, arterial blood gas analysis results, and respiratory variables were recorded.
resultsNo significant changes in hemodynamic values and rSO2 were observed during the study. Peak airway pressure was significantly lower, but mean airway pressure and dynamic compliance were significantly higher at I/E ratios of 1:1 and 2:1 than during conventional I/E ratio ventilation. Arterial oxygen tension (PaO2) value was significantly higher (p = 0.009), and alveolar-arterial oxygen tension gradient was lower (p = 0.015) at an I/E ratio of 2:1 than during conventional ratio ventilation.
conclusionsThe use of prolonged I/E ratio of 2:1 significantly improved respiratory mechanics and arterial oxygenation without causing hemodynamic derangements or cerebral desaturation during laparoscopic bariatric surgery in the reverse Trendelenburg position.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.