Evidence map›Paper›PMID 26129778›Full record

ArticleNature communications2015

SCARECROW-LIKE15 interacts with HISTONE DEACETYLASE19 and is essential for repressing the seed maturation programme.

Ming-Jun Gao, Xiang Li, Jun Huang, Gordon M Gropp, Branimir Gjetvaj, Donna L Lindsay, Shu Wei, Cathy Coutu, Zhixiang Chen, Xiao-Chun Wan and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 79 citations in OpenAlex.

  1. Histone deacetylase BrHDA19 is involved in regulating bolting time in Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  2. Review
  3. ABA-Induced Transcriptomic Dynamics inPlants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Structure-function analyses revealCurrent research in structural biology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. GWAS and transcriptome analysis reveal MADS26 involved in seed germination ability in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Ming-Jun GaoAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Xiang LiAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Jun HuangAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Gordon M GroppAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Branimir GjetvajAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Donna L LindsayDepartment of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada S7N 5E5.
Shu WeiKey Laboratory of Tea Biochemistry and Biotechnology, Anhui Agricultural University, Hefei, Anhui 230036, China.
Cathy CoutuAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Zhixiang ChenDepartment of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907, USA.
Xiao-Chun WanKey Laboratory of Tea Biochemistry and Biotechnology, Anhui Agricultural University, Hefei, Anhui 230036, China.
Abdelali HannoufaAgriculture and Agri-Food Canada, 1391 Sandford Street, London, ON, Canada N5V 4T3.
Derek J LydiateAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Margaret Y GruberAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Z Jeffrey ChenInstitute for Cellular and Molecular Biology, Center for Computational Biology and Bioinformatics, University of Texas at Austin, Austin, Texas 78712, USA.
Dwayne D HegedusAgriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon, SK, Canada S7N 0X2.
Agriculture and Agri-Food Canada · CAAnhui Agricultural University · CNPurdue University West Lafayette · USThe University of Texas at Austin · USUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic regulation of gene expression is critical for controlling embryonic properties during the embryo-to-seedling phase transition. Here we report that a histone deacetylase19 (HDA19)-associated regulator, scarecrow-like15 (SCL15), is essential for repressing the seed maturation programme in vegetative tissues. SCL15 is expressed in and GFP-tagged SCL15 predominantly localizes to, the vascular bundles particularly in the phloem companion cells and neighbouring specialized cells. Mutation of SCL15 leads to a global shift in gene expression in seedlings to a profile resembling late embryogenesis in seeds. In scl15 seedlings, many genes involved in seed maturation are markedly derepressed with concomitant accumulation of seed 12S globulin; this is correlated with elevated levels of histone acetylation at a subset of seed-specific loci. SCL15 physically interacts with HDA19 and direct targets of HDA19-SCL15 association are identified. These studies reveal that SCL15 acts as an HDA19-associated regulator to repress embryonic traits in seedlings.

Indexed as

Gene Expression Regulation, PlantArabidopsisArabidopsis ProteinsHistone DeacetylasesMutationPhenotypePlant Vascular BundleRepressor ProteinsSeedlingsSeedsTwo-Hybrid System TechniquesArabidopsis ProteinsHDA19 protein, ArabidopsisHistone DeacetylasesRepressor ProteinsSCARECROW-LIKE15 protein, Arabidopsis

Identifiers

PMID26129778
PMCPMC4507008
OpenAlexW2270936197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.