ArticleBMJ open2015
The correlation between blood pressure and kidney function decline in older people: a registry-based cohort study.
Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- A systematic review and meta-analysis of the effectiveness of hypertension interventions in faith-based organisation settings.Journal of global health · 2023Pooled it
- Economic Evaluation of the HEARTS Standardized Hypertension Treatment Program With Fixed-Dose Combination Pills in Chile Primary Care Clinics.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2025Article
- Deterioration of Kidney Function Is Affected by Central Arterial Stiffness in Late Life.Journal of clinical medicine · 2024Article
- Cardiovascular Risk Factor Control in 70- to 95-Year-Old Individuals: Cross-Sectional Results from the Population-Based AugUR Study.Journal of clinical medicine · 2023Article
- Computational Pipeline for Glomerular Segmentation and Association of the Quantified Regions with Prognosis of Kidney Function in IgA Nephropathy.Diagnostics (Basel, Switzerland) · 2022Article
- Time to Kidneys Failure Modeling in the Patients at Adama Hospital Medical College: Application of Copula Model.Journal of research in health sciences · 2022Article
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- Obesity, Weight Loss, Lifestyle Interventions, and Autosomal Dominant Polycystic Kidney Disease.Kidney and dialysis · 2022Article
- A Resampling Method to Improve the Prognostic Model of End-Stage Kidney Disease: A Better Strategy for Imbalanced Data.Frontiers in medicine · 2022Article
- Potentiality of Self-ClonedFoods (Basel, Switzerland) · 2020Article
- A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure.Kidney international · 2020Article
- Blood Pressure is Associated with Rapid Kidney Function Decline in a Very Elderly Hypertensive Chinese Population.Clinical interventions in aging · 2020Article
- Hypertension prevalence and its trend in Bangladesh: evidence from a systematic review and meta-analysis.Clinical hypertension · 2020Article
- Risk of Kidney Dysfunction from Polypharmacy among Older Patients: A Nested Case-Control Study of the South Korean Senior Cohort.Scientific reports · 2019Article
- Burden of heart failure in Flemish general practices: a registry-based study in the Intego database.BMJ open · 2019Article
- Article
- Time trends in statin use and incidence of recurrent cardiovascular events in secondary prevention between 1999 and 2013: a registry-based study.BMC cardiovascular disorders · 2018Article
- Longitudinal Blood Pressure Changes and Kidney Function Decline in Persons Without Chronic Kidney Disease: Findings From the MESA Study.American journal of hypertension · 2018Article
- Profiling of cardio-metabolic risk factors and medication utilisation among Type II diabetes patients in Ghana: a prospective cohort study.Clinical and translational medicine · 2017Article
- Prescription of Antibiotics to Treat Gonorrhoea in General Practice in Flanders 2009-2013: A Registry-Based Retrospective Cohort Study.Journal of sexually transmitted diseases · 2017Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine the relation between static and dynamic blood pressure (BP) measurements and the evolution of kidney function in older people, adjusted for the presence of multimorbidity.
designRetrospective cohort study during a 10-year time interval (2002-2012) in three age strata of patients aged 60 and older.
settingPrimary care registration network with 97 general practitioners working in 55 practices regularly submitting collected patient data.
participantsAll patients with at least one BP measurement in 2002 and at least four serum creatine measurements after 2002 (n=8636). A modified Charlson Comorbidity Index (mCCI) at baseline was registered. Change in systolic and diastolic BP (DBP) and pulse pressure (PP) from 2002 onwards was calculated. The relation between kidney function evolution and baseline BP and change in BP was examined using linear and logistic regression analysis.
main outcome measuresThe slope of the estimated glomerular filtration rate (eGFR, MDRD, Modification of Diet in Renal Disease equation) was calculated by the ordinal least square method. A rapid annual decline of kidney function was defined as ≥ 3 L/min/1.73 m(2)/year.
resultsRapid annual decline of kidney function occurred in 1130 patients (13.1%). High baseline systolic BP (SBP) and PP predicted kidney function decline in participants aged 60-79 years. No correlation between baseline BP and kidney function decline was found in participants aged 80 years and older. An annual decline of ≥ 1 mm Hg in SBP and PP was a strong risk factor for a rapid annual kidney function decline in all age strata, independent of baseline BP and mCCI. A decline in DBP as also a strong independent predictor in participants aged 60-79 years.
conclusionsThe present study identified a decline in BP over time as a strong risk factor for kidney function decline in all age strata, adjusted for mCCI and baseline kidney function and BP.
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