ArticleScientific reports2015
Redox Linked Flavin Sites in Extracellular Decaheme Proteins Involved in Microbe-Mineral Electron Transfer.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed, 164 citations in OpenAlex.
- Cell-Surface Inter-Cytochrome Electron Transfer Limits Biofilm Electron Conduction Kinetics inJournal of the American Chemical Society · 2025Article
- Extracellular catalysis of environmental substrates by Shewanella oneidensis MR-1 occurs via active sites on the C-terminal domains of MtrC.Protein science : a publication of the Protein Society · 2025Article
- Non-Respiratory Extracellular Electron Transfer Competes with Nitrogenase for Electrons in Rhodopseudomonas Palustris.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Impact of Native Environment in Multiheme-Cytochrome Chains of the MtrCAB Complex.Journal of chemical information and modeling · 2025Article
- Single-cell phenotyping of extracellular electron transfer via microdroplet encapsulation.Applied and environmental microbiology · 2025Article
- Electron transfer in multicentre redox proteins: from fundamentals to extracellular electron transfer.Bioscience reports · 2025Review
- Overlap and differences between the inward and outward electron transfer pathways in Shewanella oneidensis.FEMS microbiology letters · 2025Article
- Genetic Code Expansion inACS synthetic biology · 2024Article
- Novel Insights on Extracellular Electron Transfer Networks in theMicroorganisms · 2024Article
- Single-Cell Phenotyping of Extracellular Electron Transfer via Microdroplet Encapsulation.bioRxiv : the preprint server for biology · 2024Article
- Mechanism of Reduction of Aqueous U(V)-dpaea and Solid-Phase U(VI)-dpaea Complexes: The Role of MultihemeEnvironmental science & technology · 2023Article
- Organic buffers act as reductants of abiotic and biogenic manganese oxides.Scientific reports · 2023Article
- Article
- Deciphering Molecular Factors That Affect Electron Transfer at the Cell Surface of Electroactive Bacteria: The Case of OmcA fromMicroorganisms · 2022Article
- Review
- A New Paradigm of Multiheme Cytochrome Evolution by Grafting and Pruning Protein Modules.Molecular biology and evolution · 2022Article
- Single molecule tracking of bacterial cell surface cytochromes reveals dynamics that impact long-distance electron transport.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Significance ofBiology · 2022Review
- Extracellular Electron Transfer Enables Cellular Control of Cu(I)-Catalyzed Alkyne-Azide Cycloaddition.ACS central science · 2022Article
- Thermodynamic controls on rates of iron oxide reduction by extracellular electron shuttles.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
Extracellular microbe-mineral electron transfer is a major driving force for the oxidation of organic carbon in many subsurface environments. Extracellular multi-heme cytochromes of the Shewenella genus play a major role in this process but the mechanism of electron exchange at the interface between cytochrome and acceptor is widely debated. The 1.8 Å x-ray crystal structure of the decaheme MtrC revealed a highly conserved CX8C disulfide that, when substituted for AX8A, severely compromised the ability of S. oneidensis to grow under aerobic conditions. Reductive cleavage of the disulfide in the presence of flavin mononucleotide (FMN) resulted in the reversible formation of a stable flavocytochrome. Similar results were also observed with other decaheme cytochromes, OmcA, MtrF and UndA. The data suggest that these decaheme cytochromes can transition between highly reactive flavocytochromes or less reactive cytochromes, and that this transition is controlled by a redox active disulfide that responds to the presence of oxygen.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.