Evidence map›Paper›PMID 26126687›Full record

ReviewCurrent HIV/AIDS reports2015

The role of statins in the setting of HIV infection.

Allison Ross Eckard, Grace A McComsey

Open access · greenAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Statin Therapy Does Not Reduce Liver Fat Scores in Patients Receiving Antiretroviral Therapy for HIV Infection.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019
    Trial
  4. Review
  5. Residual Traditional Risk in Non-Traditional Atherosclerotic Diseases.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Atherosclerosis in HIV Patients: What Do We Know so Far?International journal of molecular sciences · 2022
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Statin therapy in COVID-19 infection.European heart journal. Cardiovascular pharmacotherapy · 2020
    Article
  19. Kidney Disease in HIV Infection.Journal of clinical medicine · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Allison Ross EckardDepartments of Pediatrics and Medicine, Divisions of Infectious Diseases, Medical University of South Carolina, 135 Rutledge Ave, MSC 752, Charleston, SC, 29425, USA, eckarda@musc.edu.
Grace A McComsey
Case Western Reserve University · USMedical University of South Carolina · US

Funding

Inflammation, Heart and BoneR01NR012642 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2010 to 2014
$2.5M
Vitamin D, drug metabolism, and cardiovascular complications in pediatric HIVR01HD070490 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2011 to 2015
$1.7M
Vitamin D status and HIV-related complications in children and young adultsK23HD069199 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ECKARD, ALLISON ROSS · 2012 to 2016
$631k
NICHD NIH HHS HD070490NICHD NIH HHS K23 HD069199NICHD NIH HHS R01 HD070490NINR NIH HHS R01 NR012642
6 · The paper itself

Abstract

HIV-infected individuals are at an increased risk of cardiovascular disease (CVD) and other HIV-related co-morbidities. This is due in part to dyslipidemia associated with antiretroviral therapy and increased inflammation and immune activation from chronic HIV infection. Statins not only have potent lipid-lowering properties but are also anti-inflammatory and immunomodulators. Studies suggest that statin therapy in the HIV-infected population may decrease the risk of CVD and other non-AIDS-defining co-morbidities. This review summarizes the recent literature on statin use in the HIV setting.

Indexed as

Anti-HIV AgentsAnti-Retroviral AgentsCardiovascular DiseasesDyslipidemiasHIV InfectionsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsRisk FactorsAnti-HIV AgentsAnti-Retroviral AgentsHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID26126687
PMCPMC4860807
OpenAlexW761614772

What OpenQuestion holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.