Evidence map›Paper›PMID 26126286›Full record

ArticleIEEE transactions on medical imaging2015

Automated, Depth-Resolved Estimation of the Attenuation Coefficient From Optical Coherence Tomography Data.

Gennifer T Smith, Nicholas Dwork, Daniel O'Connor, Uzair Sikora, Kristen L Lurie, John M Pauly, Audrey K Ellerbee

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

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  20. Improving the characterization ofNeurophotonics · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gennifer T Smith
Nicholas Dwork
Daniel O'Connor
Uzair Sikora
Kristen L Lurie
John M Pauly
Audrey K Ellerbee

Funding

Predoctoral Training in Biomedical Imaging at Stanford UniversityT32EB009653 · NIBIB · STANFORD UNIVERSITY · PI BUTTS-PAULY, KIM · 2010 to 2019
$2.1M
NIBIB NIH HHS T32 EB009653NIBIB NIH HHS T32EB009653
6 · The paper itself

Abstract

We present a method for automated, depth-resolved extraction of the attenuation coefficient from Optical Coherence Tomography (OCT) data. In contrast to previous automated, depth-resolved methods, the Depth-Resolved Confocal (DRC) technique derives an invertible mapping between the measured OCT intensity data and the attenuation coefficient while considering the confocal function and sensitivity fall-off, which are critical to ensure accurate measurements of the attenuation coefficient in practical settings (e.g., clinical endoscopy). We also show that further improvement of the estimated attenuation coefficient is possible by formulating image denoising as a convex optimization problem that we term Intensity Weighted Horizontal Total Variation (iwhTV). The performance and accuracy of DRC alone and DRC+iwhTV are validated with simulated data, optical phantoms, and ex-vivo porcine tissue. Our results suggest that implementation of DRC+iwhTV represents a novel way to improve OCT contrast for better tissue characterization through quantitative imaging.

Indexed as

AlgorithmsAnimalsColonImage Processing, Computer-AssistedPhantoms, ImagingSignal-To-Noise RatioSwineTomography, Optical CoherenceUrinary Bladder

Identifiers

PMID26126286
PMCPMC4714956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.