Evidence map›Paper›PMID 26125021›Full record

ReviewBioMed research international2015

Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications.

Yueh-Hsia Luo, Louis W Chang, Pinpin Lin

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 245 citations in OpenAlex.

  1. Review
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  3. Article
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  7. Designing the Next Generation of Biomaterials through Nanoengineering.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  8. Article
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  10. Article
  11. Review
  12. Green synthesizedFuture science OA · 2024
    Article
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  15. Article
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  18. Review
  19. Article
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yueh-Hsia LuoDivision of Environmental Health and Occupational Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan 35053, Miaoli County, Taiwan.
Louis W ChangNational Environmental Health Research Center, National Health Research Institutes, 35 Keyan Road, Zhunan 35053, Miaoli County, Taiwan.
Pinpin LinDivision of Environmental Health and Occupational Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan 35053, Miaoli County, Taiwan ; National Environmental Health Research Center, National Health Research Institutes, 35 Keyan Road, Zhunan 35053, Miaoli County, Taiwan.
National Health Research Institutes · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanomaterials, including metal-based nanoparticles, are used for various biological and medical applications. However, metals affect immune functions in many animal species including humans. Different physical and chemical properties induce different cellular responses, such as cellular uptake and intracellular biodistribution, leading to the different immune responses. The goals of this review are to summarize and discuss the innate and adaptive immune responses triggered by metal-based nanoparticles in a variety of immune system models.

Indexed as

Adaptive ImmunityAnimalsHumansImmunity, InnateInflammationMetal NanoparticlesTissue Distribution

Identifiers

PMID26125021
PMCPMC4466342
OpenAlexW1929089343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.