Evidence map›Paper›PMID 26124799›Full record

ArticleAfrican health sciences2015

Relation of maternal vitamin D status with gestational diabetes mellitus and perinatal outcome.

Niyazoglu Mutlu, Hatipoglu Esra, Aydogan Begum, Dellal Fatma, Yavuz Arzu, Hacioglu Yalcin, Kaya Fatih, Kumru Selahattin

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in African health sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03665974 (Lower Vitamin D Levels During Second Trimester Are Associated With Developing Gestational Diabetes Mellitus), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03665974 completednot on this map

Lower Vitamin D Levels During Second Trimester Are Associated With Developing Gestational Diabetes Mellitus: an Observational Cross-sectional Study

TypeobservationalSponsorHacettepe UniversityRan2013 to 2013Enrolled80ConditionsDeficiency, Vitamin D, Diabetes, Gestational
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Vitamin D Deficiency in Pregnant Women and Their Infants.Journal of clinical research in pediatric endocrinology · 2018
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Niyazoglu MutluDivision of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
Hatipoglu EsraDivision of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
Aydogan BegumDepartment of Obstetrics and Gynecology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
Dellal FatmaDepartment of Endocrinology and Metabolism, Ministry of Health's Ankara Ataturk Education and Research Hospital, Ankara, Turkey.
Yavuz ArzuDepartment of Obstetrics and Gynecology, Ministry of Health's Kocaeli Derince Education and Research Hospital, Kocaeli, Turkey.
Hacioglu YalcinDepartment of Internal Medicine, Ministry of Health's Istanbul Education and Research Hospital, Istanbul, Turkey.
Kaya FatihDepartment of Internal Medicine, Ministry of Health's Istanbul Education and Research Hospital, Istanbul, Turkey.
Kumru SelahattinDepartment of Obstetrics and Gynecology, Ministry of Health's Antalya Education and Research Hospital, Antalya, Turkey.
Istanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between maternal vitamin D status and glucose intolerance, and its impact on pregnant women and their newborns.

methodsA cohort of pregnant women were divided into three groups: women with gestational diabetes mellitus, ones with normal results both after the 50 gr and 100 gr OGTT (CG-1) and ones having a positive result after the 50 gr OGTT screening but negative results for gestational diabetes mellitus (GDM) after the 100 gr OGTT (CG-2).

resultsThe newborn length in CG-1 was greater than in GDM and CG-2 (p= 0.002 and p= 0.02). Fasting blood glucose and insulin resistance (IR) were negatively correlated with length of the newborns (r=-0.3, p=0.03 and r=-0.3, p=0.01). The newborns of women with GDM had lower APGAR-1 and 5 scores than those of CG-1 and CG-2 (APGAR-1 p= 0.001 and p= 0.004, APGAR-5 p=0.005 and p=0.007, respectively). APGAR scores were correlated negatively with IR (APGAR-1 r=-0.32, p=0.01, APGAR-5 r=-0.3, p=0.03) and positively with 25OHD levels (APGAR-1 r=0.3, p=0.01, APGAR-5 r=0.3, p=0.02).

conclusionVitamin D deficiency, gestational diabetes and insulin resistance are interrelated. Severe vitamin D deficiency during pregnancy is associated with poor pregnancy and neonatal outcome.

Indexed as

AdultApgar ScoreBlood GlucoseCase-Control StudiesDelivery, ObstetricDiabetes, GestationalFemaleGlucose Tolerance TestHumansInfant, NewbornInsulin ResistancePregnancyPregnancy OutcomeSocioeconomic FactorsTurkeyVitamin DBlood GlucoseVitamin DVitaminsgestational diabetesinsulin resistancepregnancy and neonatal outcomeVitamin D deficiency

Identifiers

PMID26124799
PMCPMC4480463
OpenAlexW1589643636

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.