Evidence map›Paper›PMID 26124508›Full record

Trial reportBMJ open2015

A randomised controlled trial to prevent smoking relapse among recently quit smokers enrolled in employer and health plan sponsored quitlines.

Anna M McDaniel, Katrina A Vickerman, Timothy E Stump, Patrick O Monahan, Jeffrey L Fellows, Michael T Weaver, Beatriz H Carlini, Victoria L Champion, Susan M Zbikowski

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00888992 (Technology-Enhanced Quitline Services to Prevent Smoking Relapse), which is not on this map. Cited by 8 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 6 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00888992 nacompletednot on this map

Technology-Enhanced Quitline Services to Prevent Smoking Relapse

TypeinterventionalSponsorIndiana UniversityRan2010 to 2014Enrolled1,785ConditionsSmoking CessationArmsQuitline Service + 10 automated monitoring calls, Quitline service + 20 automated monitoring calls
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Relapse prevention interventions for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. Telephone counselling for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Relapse prevention interventions for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Anna M McDanielCollege of Nursing, University of Florida, Gainesville, Florida, USA.
Katrina A VickermanAlere Wellbeing, Seattle, Washington, USA.ORCID http://orcid.org/0000-0003-3642-5265
Timothy E StumpDepartment of Biostatistics, Indiana University, School of Medicine, Indianapolis, Indiana, USA.
Patrick O MonahanDepartment of Biostatistics, Indiana University, School of Medicine, Indianapolis, Indiana, USA.
Jeffrey L FellowsKaiser Permanente Center for Health Research, Portland, Oregon, USA.
Michael T WeaverCollege of Nursing, University of Florida, Gainesville, Florida, USA.
Beatriz H CarliniAlcohol and Drug Abuse Institute, University of Washington, Seattle, Washington, USA.
Victoria L ChampionIndiana University School of Nursing, Indianapolis, Indiana, USA.
Susan M ZbikowskiAlere Wellbeing, Seattle, Washington, USA.
Alere (United Kingdom) · GBIndiana University School of MedicineUniversity of Florida · USIndiana University – Purdue University Indianapolis · USKaiser Permanente Center for Health Research · USUniversity of Washington · US

Funding

Technology-Enhanced Quitline Services to Prevent Smoking RelapseR01CA138936 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI CHAMPION, VICTORIA LEE · 2009 to 2014
$2.6M
NCI NIH HHS R01 CA138936NCI NIH HHS R01 CA138936-03
6 · The paper itself

Abstract

objectiveTo test adding an interactive voice response (IVR)-supported protocol to standard quitline treatment to prevent relapse among recently quit smokers.

designParallel randomised controlled trial with three arms: standard quitline, standard plus technology enhanced quitline with 10 risk assessments (TEQ-10), standard plus 20 TEQ assessments (TEQ-20).

settingQuit For Life (QFL) programme.

participants1785 QFL enrolees through 19 employers or health plans who were 24+ h quit.

interventionsQFL is a 5-call telephone-based cessation programme including medications and web-based support. TEQ interventions included 10 or 20 IVR-delivered relapse risk assessments over 8 weeks with automated transfer to counselling for those at risk.

main outcome measuresSelf-reported 7-day and 30-day abstinence assessed at 6-month and 12-month post-enrolment (response rates: 61% and 59%, respectively). Missing data were imputed.

results1785 were randomised (standard n=592, TEQ-10 n=602, TEQ-20 n=591). Multiple imputation-derived, intent-to-treat 30-day quit rates (95% CI) at 6 months were 59.4% (53.7% to 63.8%) for standard, 62.3% (57.7% to 66.9%) for TEQ-10, 59.4% (53.7% to 65.1%) for TEQ-20 and 30-day quit rates at 12 months were 61.2% (55.6% to 66.8%) for standard, 60.6% (56.0% to 65.2%) for TEQ-10, 54.9% (49.0% to 60.9%) for TEQ-20. There were no significant differences in quit rates. 73.3% of TEQ participants were identified as at-risk by IVR assessments; on average, participants completed 0.41 IVR-transferred counselling calls. Positive risk assessments identified participants less likely (OR=0.56, 95% CI 0.42 to 0.76) to be abstinent at 6 months.

conclusionsStandard treatment was highly effective, with 61% remaining abstinent at 12 months using multiple imputation intent-to-treat (intent-to-treat missing=smoking quit rate: 38%). TEQ assessments identified quitters at risk for relapse. However, adding IVR-transferred counselling did not yield higher quit rates. Research is needed to determine if alternative designs can improve outcomes. TRIAL REGISTRATION NUMBER: NCT00888992.

Indexed as

HotlinesInsurance, HealthAdultCounselingFemaleFollow-Up StudiesHealth Benefit Plans, EmployeeHumansMaleProgram EvaluationRecurrenceSmokingSmoking CessationTreatment OutcomeInteractive Voice ResponseIVRquitlinesrelapse preventionsmoking

Identifiers

PMID26124508
PMCPMC4486943
OpenAlexW2112202348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.