Evidence map›Paper›PMID 26124151›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2015

Expression quantitative trait loci regulate HNF4A and PTBP1 expression in human brains.

Guiyou Liu, Xinjie Bao, Renzhi Wang

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. PTBP1 as a potential regulator of disease.Molecular and cellular biochemistry · 2024
    Review
  4. Article
  5. Article
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  13. Autoimmune disease variants regulateProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  14. Rs4878104 contributes to Alzheimer's disease risk and regulates DAPK1 gene expression.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
    Article
  15. Cis-eQTLs regulate reduced LST1 gene and NCR3 gene expression and contribute to increased autoimmune disease risk.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  16. Reply to Liu et al.: HNF4A and PTBP1 expression in the brain of neurodegenerative disease patients.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Guiyou LiuGenome Analysis Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China; liuguiyou1981@163.com.
Xinjie BaoDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Renzhi WangDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersHepatocyte Nuclear Factor 4Heterogeneous-Nuclear RibonucleoproteinsHumansParkinson DiseasePolypyrimidine Tract-Binding ProteinBiomarkersHepatocyte Nuclear Factor 4Heterogeneous-Nuclear RibonucleoproteinsPolypyrimidine Tract-Binding Protein

Identifiers

PMID26124151
PMCPMC4522784
OpenAlexW1956212565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.