ArticleProceedings of the National Academy of Sciences of the United States of America2015
Drosophila circadian rhythms in seminatural environments: Summer afternoon component is not an artifact and requires TrpA1 channels.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Mating imperatives drive plasticity of the daily temporal niche in fruit flies.Nature ecology & evolution · 2026Article
- Behavioral adaptation to warm conditions via Lim1-mediated acceleration of neuronal clocks.Nature neuroscience · 2026Article
- Automated long-term field monitoring reveals diel and seasonal activity patterns of Drosophila suzukii.PloS one · 2026Article
- Neuropeptide dynamics coordinate layered plasticity mechanisms adaptingScience advances · 2025Article
- Temperature-dependent modulation of light-induced circadian responses in Drosophila melanogaster.The EMBO journal · 2025Article
- The physiological role of TRP channels in sleep and circadian rhythm.Journal of cellular and molecular medicine · 2024Review
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- Genetic correlation between aggressive signals and fighting.Biology letters · 2023Article
- Article
- Mating disrupts morning anticipation in Drosophila melanogaster females.PLoS genetics · 2022Article
- Animal behavior is central in shaping the realized diel light niche.Communications biology · 2022Article
- Circadian Clock Genes Regulate Temperature-Dependent Diapause Induction in SilkwormFrontiers in physiology · 2022Article
- Article
- Perception of Daily Time: Insights from the Fruit Flies.Insects · 2021Review
- The Panopticon-Assessing the Effect of Starvation on Prolonged Fly Activity and Place Preference.Frontiers in behavioral neuroscience · 2021Article
- Peripheral Sensory Organs Contribute to Temperature Synchronization of the Circadian Clock inFrontiers in physiology · 2021Review
- Intrapopulation genetic variation in the level and rhythm of daily activity inEcology and evolution · 2020Article
- Article
- The Summer Is Coming:Frontiers in physiology · 2020Article
- Model and Non-model Insects in Chronobiology.Frontiers in behavioral neuroscience · 2020Review
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Authors and funding
9 authors.
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Abstract
Under standard laboratory conditions of rectangular light/dark cycles and constant warm temperature, Drosophila melanogaster show bursts of morning (M) and evening (E) locomotor activity and a "siesta" in the middle of the day. These M and E components have been critical for developing the neuronal dual oscillator model in which clock gene expression in key cells generates the circadian phenotype. However, under natural European summer conditions of cycling temperature and light intensity, an additional prominent afternoon (A) component that replaces the siesta is observed. This component has been described as an "artifact" of the TriKinetics locomotor monitoring system that is used by many circadian laboratories world wide. Using video recordings, we show that the A component is not an artifact, neither in the glass tubes used in TriKinetics monitors nor in open-field arenas. By studying various mutants in the visual and peripheral and internal thermo-sensitive pathways, we reveal that the M component is predominantly dependent on visual input, whereas the A component requires the internal thermo-sensitive channel transient receptor potential A1 (TrpA1). Knockdown of TrpA1 in different neuronal groups reveals that the reported expression of TrpA1 in clock neurons is unlikely to be involved in generating the summer locomotor profile, suggesting that other TrpA1 neurons are responsible for the A component. Studies of circadian rhythms under seminatural conditions therefore provide additional insights into the molecular basis of circadian entrainment that would otherwise be lost under the usual standard laboratory protocols.
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