ArticleProceedings of the National Academy of Sciences of the United States of America2015
Triangulation of the neurocomputational architecture underpinning reading aloud.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Randomized trial of iReadMore word reading training and brain stimulation in central alexia.Brain : a journal of neurology · 2018Trial
- The reading brain - Transforming vision into language.Progress in neurobiology · 2026Review
- The Role of the Anterior Temporal Lobe in Reading: An HD-tDCS Study.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Meaning for reading: the neurocognitive basis of semantic reading impairment after stroke.Brain : a journal of neurology · 2025Article
- Irregular word reading as a marker of semantic decline in Alzheimer's disease: implications for premorbid intellectual ability measurement.Alzheimer's research & therapy · 2024Article
- Modelling individual differences in reading using an optimised MikeNet simulator: the impact of reading instruction.Frontiers in human neuroscience · 2024Article
- Distinct parallel activation and interaction between dorsal and ventral pathways during phonological and semantic processing: A cTBS-fMRI study.Human brain mapping · 2024Article
- Irregular word reading as a marker of cognitive and semantic decline in Alzheimer's disease rather than an estimate of premorbid intellectual abilities.Research square · 2023Article
- Distance-dependent distribution thresholding in probabilistic tractography.Human brain mapping · 2023Article
- A Semantic Cognition Contribution to Mood and Anxiety Disorder Pathophysiology.Healthcare (Basel, Switzerland) · 2023Review
- The influence of oral vocabulary knowledge on individual differences in a computational model of reading.Scientific reports · 2023Article
- Task modulates the orthographic and phonological representations in the bilateral ventral Occipitotemporal cortex.Brain imaging and behavior · 2022Article
- Preventing Children From Developing Dyslexia: A Premature Writing Hypothesis.Perceptual and motor skills · 2022Article
- Using electrophysiological correlates of early semantic priming to test models of reading aloud.Scientific reports · 2022Article
- Individuals' preference on reading pathways influences the involvement of neural pathways in phonological learning.Frontiers in psychology · 2022Article
- Is there evidence for a noisy computation deficit in developmental dyslexia?Frontiers in human neuroscience · 2022Article
- White matter disconnectivity fingerprints causally linked to dissociated forms of alexia.Communications biology · 2021Article
- Category-selective deficits are the exception and not the rule: Evidence from a case-series of 64 patients with ventral occipito-temporal cortex damage.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- Functional connectivity in the developing language network in 4-year-old children predicts future reading ability.Developmental science · 2021Article
- Individual differences in learning the regularities between orthography, phonology and semantics predict early reading skills.Journal of memory and language · 2020Article
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Authors and funding
3 authors.
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Abstract
The goal of cognitive neuroscience is to integrate cognitive models with knowledge about underlying neural machinery. This significant challenge was explored in relation to word reading, where sophisticated computational-cognitive models exist but have made limited contact with neural data. Using distortion-corrected functional MRI and dynamic causal modeling, we investigated the interactions between brain regions dedicated to orthographic, semantic, and phonological processing while participants read words aloud. We found that the lateral anterior temporal lobe exhibited increased activation when participants read words with irregular spellings. This area is implicated in semantic processing but has not previously been considered part of the reading network. We also found meaningful individual differences in the activation of this region: Activity was predicted by an independent measure of the degree to which participants use semantic knowledge to read. These characteristics are predicted by the connectionist Triangle Model of reading and indicate a key role for semantic knowledge in reading aloud. Premotor regions associated with phonological processing displayed the reverse characteristics. Changes in the functional connectivity of the reading network during irregular word reading also were consistent with semantic recruitment. These data support the view that reading aloud is underpinned by the joint operation of two neural pathways. They reveal that (i) the ATL is an important element of the ventral semantic pathway and (ii) the division of labor between the two routes varies according to both the properties of the words being read and individual differences in the degree to which participants rely on each route.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.