Evidence map›Paper›PMID 26123955›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Baylisascaris procyonis and Herpes Simplex Virus 2 Coinfection Presenting as Ocular Larva Migrans with Granuloma Formation in a Child.

Grace Liu, Glenn Fennelly, Kevin R Kazacos, Charles Grose, Joanna Dobroszycki, Norman Saffra, Christina M Coyle, Louis M Weiss, Moshe M Szlechter, Herbert B Tanowitz

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Human infections with the raccoon roundworm,The Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Grace LiuDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Glenn FennellyDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Kevin R KazacosDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Charles GroseDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Joanna DobroszyckiDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Norman SaffraDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Christina M CoyleDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Louis M WeissDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Moshe M SzlechterDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa.
Herbert B TanowitzDepartment of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa herbert.tanowitz@einstein.yu.edu.
Albert Einstein College of Medicine · US

Funding

Autophagy and ER stress during varicella infectionR01AI089716 · NIAID · UNIVERSITY OF IOWA · PI GROSE, CHARLES F. · 2011 to 2015
$1.9M
NIAID NIH HHS AI-89716NIAID NIH HHS R01 AI089716
6 · The paper itself

Abstract

Ocular Baylisascaris procyonis infection results from ingestion of infective eggs of B. procyonis, the raccoon ascarid. Herpes simplex virus type 2 (HSV-2) infection of the retina is the result of either primary infection or reactivated disease. Herein, we report a case of a 12-year-old female resident of the Bronx in New York City, who presented with pan-uveitis and vision loss. Initial evaluation for etiologic causes was nondiagnostic. Serology for anti-Baylisascaris procyonis antibodies in serum and vitreous fluid were both positive. Polymerase chain reaction (PCR) of vitreous fluid was positive for HSV-2. Treatment with vitrectomy, albendazole, and acyclovir resulted in mild improvement of visual acuity. The atypical presentation of B. procyonis in this case, as ocular larva migrans with a peripheral granuloma and retinal detachment, underscores the importance of maintaining a high degree of suspicion for this pathogen even in non-diffuse unilateral subacute neuroretinitis (DUSN) patients in urban areas. This case further illustrates that it is possible to have coexisting infections in cases of posterior uveitis.

Indexed as

AscaridoideaAnimalsAscaridida InfectionsChildCoinfectionDiagnosis, DifferentialEye Infections, ParasiticFemaleFundus OculiGranulomaHerpesvirus 2, HumanHumansKeratitis, HerpeticLarva Migrans

Identifiers

PMID26123955
PMCPMC4559706
OpenAlexW2279966327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.