Evidence map›Paper›PMID 26123947›Full record

ReviewDrugs & aging2015

Therapeutic Strategies to Treat Dry Eye in an Aging Population.

Nisreen S Ezuddin, Karam A Alawa, Anat Galor

Open access · greenAbstract readReview
In one paragraph

Review in Drugs & aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Glaucoma therapy: preservative-free for all?Clinical ophthalmology (Auckland, N.Z.) · 2018
    Review
  9. Neuropathic pain and dry eye.The ocular surface · 2018
    Review
  10. Article
  11. Article
  12. Intense pulsed light for evaporative dry eye disease.Clinical ophthalmology (Auckland, N.Z.) · 2017
    Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nisreen S EzuddinBascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Karam A Alawa
Anat Galor
University of Miami · USUnited States Department of Veterans Affairs · US

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Abigail S Hackam · 2004 to 2026
$12.2M
NEUROPATHIC PAIN: A CRITICAL MISSING PIECE IN DRY EYE?I01CX001089 · VA · MIAMI VA HEALTH CARE SYSTEM · PI GALOR, ANAT · 2016 to 2019
–
CSRD VA I01 CX001089NEI NIH HHS P30 EY014801NEI NIH HHS P30EY014801
6 · The paper itself

Abstract

Dry eye (DE) is a prevalent ocular disease that primarily affects the elderly. Affecting up to 30% of adults aged 50 years and older, DE affects both visual function and quality of life. Symptoms of DE, including ocular pain (aching, burning), visual disturbances, and tearing, can be addressed with therapeutic agents that target dysfunction of the meibomian glands, lacrimal glands, goblet cells, ocular surface, and/or neural network. This review provides an overview of the efficacy, use, and limitations of current therapeutic interventions being used to treat DE.

Indexed as

Age FactorsAgingAnimalsDry Eye SyndromesHumans

Identifiers

PMID26123947
PMCPMC4519372
OpenAlexW754077960

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.