Evidence map›Paper›PMID 26123830›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2016

Safety of symptom-limited exercise testing in a big cohort of a modern ICD population.

Frederik Voss, Melanie Schueler, Michael Lauterbach, Alexander Bauer, Hugo A Katus, Ruediger Becker

Abstract read
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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Is there any benefit using low-intensity inspiratory and peripheral muscle training in heart failure? A randomized clinical trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2017
    Trial
  3. Trial
  4. Effects of chronic carotid baroreceptor activation on arterial stiffness in severe heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2016
    Trial
  5. Article
  6. Article
  7. Review
  8. Prognostic impact of recurrences of ventricular tachyarrhythmias and appropriate ICD therapies in a high-risk ICD population.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
  9. Warm water immersion in patients with chronic heart failure: a pilot study : Shah immerse: HF.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Frederik VossDepartment of Cardiology, Krankenhaus der Barmherzigen Brueder Trier, Nordallee 1, 54290, Trier, Germany. f.voss@bk-trier.de.
Melanie SchuelerDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Michael LauterbachDepartment of Cardiology, Krankenhaus der Barmherzigen Brueder Trier, Nordallee 1, 54290, Trier, Germany.
Alexander BauerDepartment of Cardiology, Diakonie-Klinikum Schwaebisch Hall, Diakoniestr. 10, 74523, Schwaebisch Hall, Germany.
Hugo A KatusDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Ruediger BeckerDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Heidelberg University · DEKrankenhaus der Barmherzigen Brüder Trier · DEEvangelisches Diakoniekrankenhaus · DEHeidelberg University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise may predispose to ventricular arrhythmias especially in patients with congestive heart failure. As therapy with implanted cardioverter-defibrillators (ICDs) has become standard medical care, there is an emerging number of exercise tests that need to be performed in patients with ICDs. In contrast, little is known about the safety of symptom-limited exercise testing in these patients. METHODS AND

results400 ICD patients performed symptom-limited exercise treadmill testing. 200 patients performed a ramp protocol with an initial workload of 0 W increased by 15 W every minute. Another 200 ICD patients did a slightly modified ramp protocol with again an initial workload of 0 W but with an increased capacity of 15 W every 2 min. The study population consists mainly of patients with ischemic (63%) and non-ischemic (34%) heart disease. Atrial fibrillation was present in 16% of the subjects. The mean ejection fraction was 28 ± 8, and 78% of the patients had an ejection fraction below 30%. In this cohort of patients, no sustained ventricular arrhythmias and no deaths occurred during or after exercise testing. No inappropriate shock delivery was observed. The modified ramp protocol resulted in a prolonged exercise time with equal exercise capacity but does not result in an enhanced susceptibility for ventricular arrhythmias.

conclusionsSymptom-limited exercise treadmill testing in heart failure patients with ICDs is a safe procedure. The use of a ramp protocol is sufficient in terms of safety and is easy to perform in general practice. The exercise duration in heart failure patients with ICDs does not predict serious adverse events.

Indexed as

Defibrillators, ImplantableAgedAtrial FibrillationExercise TestFemaleHeart FailureHumansMaleMiddle AgedExercise testICDVentricular arrhythmias

Identifiers

PMID26123830
OpenAlexW801381407

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.