ArticleBMC genomics2015
Tobacco drought stress responses reveal new targets for Solanaceae crop improvement.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 98 citations in OpenAlex.
- Drought-Driven Divergence in Photosynthetic Performance Between TwoPlants (Basel, Switzerland) · 2025Article
- Genome-wide identification and expression analysis ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Tobacco (Frontiers in plant science · 2025Article
- Integrated miRNA and mRNA Transcriptome Analysis Reveals Regulatory Mechanisms in the Response of WinterInternational journal of molecular sciences · 2024Article
- Emerging Roles of Receptor-like Protein Kinases in Plant Response to Abiotic Stresses.International journal of molecular sciences · 2023Review
- Article
- Cross-species predictive modeling reveals conserved drought responses between maize and sorghum.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Mechanistic basis for mitigating drought tolerance by selenium application in tobacco (Frontiers in plant science · 2023Article
- Analysis of QTL mapping for germination and seedling response to drought stress in sunflower (PeerJ · 2023Article
- Impact ofPlants (Basel, Switzerland) · 2022Article
- Reprogramming of Plant Central Metabolism in Response to Abiotic Stresses: A Metabolomics View.International journal of molecular sciences · 2022Review
- Desiccation Tolerance inPlants (Basel, Switzerland) · 2022Article
- Unravelling the treasure trove of drought-responsive genes in wild-type peanut through transcriptomics and physiological analyses of root.Functional & integrative genomics · 2022Article
- Capsicum Leaves under Stress: Using Multi-Omics Analysis to Detect Abiotic Stress Network of Secondary Metabolism in Two Species.Antioxidants (Basel, Switzerland) · 2022Article
- Transcriptomic and metabolic regulatory network characterization of drought responses in tobacco.Frontiers in plant science · 2022Article
- Metabolomics and Molecular Approaches Reveal Drought Stress Tolerance in Plants.International journal of molecular sciences · 2021Review
- ThePhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Modulation of photosynthesis and other proteins during water-stress.Molecular biology reports · 2021Review
- Overexpression of A Biotic Stress-InducibleInternational journal of molecular sciences · 2021Article
- Genome-wide analysis of long non-coding RNAs (lncRNAs) in two contrasting rapeseed (Brassica napus L.) genotypes subjected to drought stress and re-watering.BMC plant biology · 2020Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Solanaceae are an economically important family of plants that include tobacco (Nicotiana tabacum L.), tomato, and potato. Drought is a major cause of crop losses.
resultsWe have identified major changes in physiology, metabolites, mRNA levels, and promoter activities during the tobacco response to drought. We have classified these as potential components of core responses that may be common to many plant species or responses that may be family/species-specific features of the drought stress response in tobacco or the Solanaceae. In tobacco the largest increase in any metabolite was a striking 70-fold increase in 4-hydroxy-2-oxoglutaric acid (KHG) in roots that appears to be tobacco/Solanaceae specific. KHG is poorly characterized in plants but is broken down to pyruvate and glyoxylate after the E. coli SOS response to facilitate the resumption of respiration. A similar process in tobacco would represent a mechanism to restart respiration upon water availability after drought. At the mRNA level, transcription factor gene induction by drought also showed both core and species/family specific responses. Many Group IX Subgroup 3 AP2/ERF transcription factors in tobacco appear to play roles in nicotine biosynthesis as a response to herbivory, whereas their counterparts in legume species appear to play roles in drought responses. We observed apparent Solanaceae-specific drought induction of several Group IId WRKY genes. One of these, NtWRKY69, showed ABA-independent drought stress-inducible promoter activity that moved into the leaf through the vascular tissue and then eventually into the surrounding leaf cells.
conclusionsWe propose components of a core metabolic response to drought stress in plants and also show that some major responses to drought stress at the metabolome and transcriptome levels are family specific. We therefore propose that the observed family-specific changes in metabolism are regulated, at least in part, by family-specific changes in transcription factor activity. We also present a list of potential targets for the improvement of Solanaceae drought responses.
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