ArticleThe European physical journal. E, Soft matter2015
Shear-enhanced adsorption of a homopolymeric globule mediated by surface catch bonds.
Article in The European physical journal. E, Soft matter, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The interplay between adsorption and aggregation of von Willebrand factor chains in shear flows.Biophysical journal · 2023Article
- Shear-Induced Extensional Response Behaviors of Tethered von Willebrand Factor.Biophysical journal · 2019Article
- Article
- Coarse-Grain Modeling of Shear-Induced Binding between von Willebrand Factor and Collagen.Biophysical journal · 2018Article
- Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor.Data in brief · 2016Article
- Internal tension in a collapsed polymer under shear flow and the connection to enzymatic cleavage of von Willebrand factor.The European physical journal. E, Soft matter · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The adsorption of a single collapsed homopolymer onto a planar smooth surface in shear flow is investigated by means of Brownian hydrodynamics simulation. While cohesive intra-polymer forces are modeled by Lennard-Jones potentials, surface-monomer interactions are described by stochastic bonds whose two-state kinetics is characterized by three parameters: bond formation rate, bond dissociation rate and an effective catch bond parameter that describes how the force acting on a surface-monomer bond influences the dissociation rate. We construct adsorption state diagrams as a function of shear rate and all three surface-monomer bond parameters. We find shear-induced adsorption in a small range of parameters for low dissociation and association rates and only when the surface-monomer bond is near the transition between slip and catch bond behavior. By mapping on a simple surface-monomer interaction model with conservative pair potentials we try to estimate the conservative potential parameters necessary to observe shear-induced surface adsorption phenomena.
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Registered trials
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