Evidence map›Paper›PMID 26123122›Full record

ArticleScientific reports2015

Early versus delayed laparoscopic common bile duct exploration for common bile duct stone-related nonsevere acute cholangitis.

Bin Zhu, Dan Li, Yu Ren, Ying Li, Yan Wang, Kai Li, Buhe Amin, Ke Gong, Yiping Lu, Ming Song and 1 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Timing of intervention: Assessing earlyWorld journal of gastrointestinal endoscopy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Bin ZhuLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Dan LiLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Yu RenLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Ying LiLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Yan WangLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Kai LiLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Buhe AminLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Ke GongLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Yiping LuLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Ming SongDepartment of medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Louisville School of Medicine, Louisville, Kentucky, US.
Nengwei ZhangLaparoscopic Surgical Center, Department of General Surgery of Beijing Shijitan Hospital, Capital Medical University. Tieyilu 10, Yangfangdian, Haidian District, Beijing 100038, P.R. China.
Beijing Shijitan Hospital · CNCapital Medical University · CNUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is undetermined when and how laparoscopic common bile duct exploration (LCBDE) should be used in patients with common bile duct (CBD) stone-related nonsevere acute cholangitis. We aimed to evaluate the effect of LCBDE on the clinical outcome of those patients within (early) or beyond (delayed) 72 hours of emergent admission. Surgery-related complications, length of hospital stay (LOS), and total cost, as well as demographic and clinical parameters were compared between the two groups. Finally, 3 and 5 patients in early and delayed LCBDE group, respectively, had retained stones, which were removed by choledochoscopy before T-tube was removed. Each group had 3 patients who developed biliary leak, which was conservatively cured by the drainage. Shorter LOS and less total cost were observed in early group compared to the late one (13.34 ± 4.48 vs. 18.32 ± 9.13, p < 0.05; 17712 ± 5446.63 vs. 21776 ± 7230.41 ¥RMB, p < 0.05). Improvement of cholangitis was achieved in all patients with LCBDE. None of the patients developed stricture of the CBD after LCBDE. To conclude, both early and delayed LCBDE are safe and effective for the treatment of CBD stone-related nonsevere acute cholangitis during emergent admissions. Early LCBDE may be superior to delayed procedure due to the shorter LOS and less cost.

Indexed as

Acute DiseaseAdultAgedCholangitisCommon Bile DuctFemaleGallstonesHumansLaparoscopyMaleMiddle AgedRetrospective StudiesTreatment Outcome

Identifiers

PMID26123122
PMCPMC4485235
OpenAlexW2262558181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.