Evidence map›Paper›PMID 26123010›Full record

ArticleJournal of autism and developmental disorders2015

Autism Symptoms Across Adulthood in Men with Fragile X Syndrome: A Cross-Sectional Analysis.

Sigan L Hartley, Anne C Wheeler, Marsha R Mailick, Melissa Raspa, Iulia Mihaila, Ellen Bishop, Donald B Bailey

Abstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sigan L HartleyHuman Development and Family Studies and Waisman Center, University of Wisconsin-Madison, 1500 Highland Ave., Madison, WI, 53705, USA. hartley@waisman.wisc.edu.
Anne C WheelerRTI International, Research Triangle Park, NC, USA.
Marsha R MailickWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Melissa RaspaRTI International, Research Triangle Park, NC, USA.
Iulia MihailaHuman Development and Family Studies, University of Wisconsin-Madison, Madison, WI, USA.
Ellen BishopRTI International, Research Triangle Park, NC, USA.
Donald B BaileyRTI International, Research Triangle Park, NC, USA.
RTI International · USUniversity of Wisconsin–Madison · US

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 1985 to 2015
$25.2M
Cooperative Agreement for a Nat'l Research & Training Org for People with DevelopU01DD000231 · DD · ASSN OF UNIVERSITY CENTERS/ DISABILITIES · PI JESIEN, GEORGE S. · 2007 to 2012
$16.8M
NCBDD CDC HHS U01 DD000231NICHD NIH HHS P30 HD003352NICHD NIH HHS P30 HD03352
6 · The paper itself

Abstract

A cross-sectional analysis was used to examine age-related differences in ASD symptoms and corresponding differences in disruptive behavior and social skills in 281 adult men with fragile X syndrome. Four age groups were created: 18-21, 22-29, 30-39, and 40-49 years. The 18-21 year-old group was reported to have more impairments in verbal communication than the 22-29 year-old group and more restricted and repetitive behaviors than the 40-49 year-old group. There was not an age-group difference in the percentage of men who met criteria for an ASD diagnosis based on respondent-reported, current symptoms. There was a trend for an age-related difference in disruptive behavior. Findings add to understanding of the developmental trajectory of ASD symptoms in adulthood.

Indexed as

AdolescentAdultAgingAutism Spectrum DisorderCommunicationCross-Sectional StudiesFragile X SyndromeHumansMaleMiddle AgedProblem BehaviorSocial SkillsYoung AdultAdultAgingAutismDSMFragile X syndrome

Identifiers

PMID26123010
PMCPMC4609597
OpenAlexW833499480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.