Evidence map›Paper›PMID 26123008›Full record

Trial reportJournal of autism and developmental disorders2015

Preschoolers with Autism Spectrum Disorder Followed for 2 Years: Those Who Gained and Those Who Lost the Most in Terms of Adaptive Functioning Outcome.

Åsa Hedvall, Joakim Westerlund, Elisabeth Fernell, Fritjof Norrelgen, Liselotte Kjellmer, Martina Barnevik Olsson, Lotta Höglund Carlsson, Mats A Eriksson, Eva Billstedt, Christopher Gillberg

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Overall prognosis of preschool autism spectrum disorder diagnoses.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Autism under the umbrella of ESSENCE.Frontiers in psychiatry · 2023
    Article
  7. Examining Predictors of Different ABA Treatments: A Systematic Review.Behavioral sciences (Basel, Switzerland) · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Physical health in children with neurodevelopmental disorders.Journal of autism and developmental disorders · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Åsa HedvallGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden. asa.lundholm-hedvall@gnc.gu.se.
Joakim WesterlundDepartment of Psychology, Stockholm University, Stockholm, Sweden.
Elisabeth FernellGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden.
Fritjof NorrelgenGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden.
Liselotte KjellmerGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden.
Martina Barnevik OlssonGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden.
Lotta Höglund CarlssonGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden.
Mats A ErikssonGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden.
Eva BillstedtGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden. eva.billstedt@gnc.gu.se.
Christopher GillbergGillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 411 19, Gothenburg, Sweden.
University of Gothenburg · SEKarolinska Institutet · SEKarolinska University Hospital · SESkaraborg Hospital · SEStockholm University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical predictors of 2-year outcome in preschoolers with ASD were studied in a population-based group of very young children with ASD (n = 208). Children who gained the most (n = 30) and lost the most (n = 23), i.e., increased or decreased their adaptive functioning outcome according to the Vineland Composite Score between study entry (T1) and follow-up (T2), 2 years later were compared. Individual factors that differed significantly between the two outcome groups were cognitive level, age at referral, not passing expected milestones at 18 months, autistic type behavior problems and regression. However, logistic regression analysis showed that only cognitive level at T1 (dichotomized into IQ < 70 and IQ ≥ 70) made a unique statistically significant contribution to outcome prediction (p = <.001) with an odds ratio of 18.01. The findings have significant clinical implications in terms of information at diagnosis regarding clinical prognosis in ASD.

Indexed as

Behavior TherapyChild DevelopmentOutcome Assessment, Health CareAutism Spectrum DisorderChildChild, PreschoolCognitionFemaleFollow-Up StudiesHealth StatusHumansIntelligenceLanguage DevelopmentMalePrognosisAutism spectrum disorderClinical characteristicsOutcomePredictorsPreschool children

Identifiers

PMID26123008
OpenAlexW838553990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.