Evidence map›Paper›PMID 26122384›Full record

Trial reportThe American journal of sports medicine2015

Risk of anterior cruciate ligament fatigue failure is increased by limited internal femoral rotation during in vitro repeated pivot landings.

Mélanie L Beaulieu, Edward M Wojtys, James A Ashton-Miller

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of sports medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The ankle syndesmosis pivot shift "Are we reviving the ACL story?"Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. An Anterior Cruciate Ligament Failure Mechanism.The American journal of sports medicine · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Quantitative comparison of the microscopic anatomy of the human ACL femoral and tibial entheses.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mélanie L BeaulieuSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA mbeaulie@umich.edu.
Edward M WojtysDepartment of Orthopaedic Surgery and MedSport, University of Michigan, Ann Arbor, Michigan, USA.
James A Ashton-MillerSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan, USA Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
University of Michigan–Ann Arbor · US

Funding

New Perspectives on ACL InjuryR01AR054821 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ASHTON-MILLER, JAMES ANTHONY, WOJTYS, EDWARD M · 2007 to 2021
$3.1M
NIAMS NIH HHS R01 AR054821
6 · The paper itself

Abstract

backgroundA reduced range of hip internal rotation is associated with increased peak anterior cruciate ligament (ACL) strain and risk for injury. It is unknown, however, whether limiting the available range of internal femoral rotation increases the susceptibility of the ACL to fatigue failure. HYPOTHESIS: Risk of ACL failure is significantly greater in female knee specimens with a limited range of internal femoral rotation, smaller femoral-ACL attachment angle, and smaller tibial eminence volume during repeated in vitro simulated single-leg pivot landings. STUDY

designControlled laboratory study.

methodsA custom-built testing apparatus was used to simulate repeated single-leg pivot landings with a 4×-body weight impulsive load that induces knee compression, knee flexion, and internal tibial torque in 32 paired human knee specimens from 8 male and 8 female donors. These test loads were applied to each pair of specimens, in one knee with limited internal femoral rotation and in the contralateral knee with femoral rotation resisted by 2 springs to simulate the active hip rotator muscles' resistance to stretch. The landings were repeated until ACL failure occurred or until a minimum of 100 trials were executed. The angle at which the ACL originates from the femur and the tibial eminence volume were measured on magnetic resonance images.

resultsThe final Cox regression model (P = .024) revealed that range of internal femoral rotation and sex of donor were significant factors in determining risk of ACL fatigue failure. The specimens with limited range of internal femoral rotation had a failure risk 17.1 times higher than did the specimens with free rotation (P = .016). The female knee specimens had a risk of ACL failure 26.9 times higher than the male specimens (P = .055).

conclusionLimiting the range of internal femoral rotation during repetitive pivot landings increases the risk of an ACL fatigue failure in comparison with free rotation in a cadaveric model. CLINICAL RELEVANCE: Screening for restricted internal rotation at the hip in ACL injury prevention programs as well as in individuals with ACL injuries and/or reconstructions is warranted.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate LigamentBiomechanical PhenomenaBody WeightCadaverFatigueFemaleFemurHumansKnee InjuriesKnee JointMaleMiddle AgedMuscle, SkeletalRisk FactorsRotationanterior cruciate ligamentfatiguefemoroacetabular impingementhipknee

Identifiers

PMID26122384
PMCPMC4615705
OpenAlexW2187207152

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.