Evidence map›Paper›PMID 26122202›Full record

ArticleEuropean child & adolescent psychiatry2016

Comorbidity and correlates of disruptive mood dysregulation disorder in 6-8-year-old children with ADHD.

Melissa Mulraney, Elizabeth J Schilpzand, Philip Hazell, Jan M Nicholson, Vicki Anderson, Daryl Efron, Timothy J Silk, Emma Sciberras

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In one paragraph

Article in European child & adolescent psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  17. Irritability and its relationships with psychological symptoms in adolescents with migraine: a case-control study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Melissa MulraneyMurdoch Childrens Research Institute, Parkville, VIC, Australia. melissa.mulraney@mcri.edu.au.
Elizabeth J SchilpzandMurdoch Childrens Research Institute, Parkville, VIC, Australia.
Philip HazellDiscipline of Psychiatry, Sydney Medical School, Sydney, NSW, Australia.
Jan M NicholsonMurdoch Childrens Research Institute, Parkville, VIC, Australia.
Vicki AndersonMurdoch Childrens Research Institute, Parkville, VIC, Australia.
Daryl EfronMurdoch Childrens Research Institute, Parkville, VIC, Australia.
Timothy J SilkMurdoch Childrens Research Institute, Parkville, VIC, Australia.
Emma SciberrasMurdoch Childrens Research Institute, Parkville, VIC, Australia.
Murdoch Children's Research Institute · AULa Trobe University · AUUniversity of Melbourne · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to characterize the nature and impact of disruptive mood dysregulation disorder (DMDD) in children with attention-deficit/hyperactivity disorder (ADHD) including its co-occurrence with other comorbidities and its independent influence on daily functioning. Children with ADHD (6-8 years) were recruited through 43 Melbourne schools, using a 2-stage screening (parent and teacher Conners 3 ADHD index) and case-confirmation (Diagnostic Interview Schedule for Children, Version IV; [DISC-IV]) procedure. Proxy DMDD diagnosis was confirmed via items from the oppositional defiant disorder (ODD) and major depressive disorder modules of the DISC-IV. Outcome domains included comorbid mental health disorders, academic functioning, social functioning, child and family quality of life, parent mental health, and parenting behaviors. Unadjusted and adjusted linear and logistic regression were used to compare children with comorbid ADHD and DMDD and children with ADHD without DMDD. Thirty-nine out of 179 children (21.8 %) with ADHD had comorbid DMDD. Children with ADHD and DMDD had a high prevalence of ODD (89.7 %) and any anxiety disorder (41.0 %). Children with ADHD and DMDD had poorer self-control and elevated bullying behaviors than children with ADHD without DMDD. Children with ADHD and DMDD were similar to children with ADHD in the other domains measured when taking into account other comorbidities including ODD. One in five children with ADHD in their second year of formal schooling met criteria for DMDD. There was a very high diagnostic overlap with ODD; however, the use of a proxy DMDD diagnosis containing items from the ODD module of the DISC-IV may have artificially inflated the comorbidity rates. DMDD added to the burden of ADHD particularly in the area of social functioning.

Indexed as

AnimalsAttention Deficit and Disruptive Behavior DisordersAttention Deficit Disorder with HyperactivityChick EmbryoChildChild BehaviorChild, PreschoolComorbidityFemaleHumansMaleMental HealthMood DisordersPrevalenceProblem BehaviorQuality of LifeAttention-deficit/hyperactivity disorderComorbiditiesDisruptive mood dysregulation disorderQuality of lifeSocial functioning

Identifiers

PMID26122202
OpenAlexW1935474552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.