Evidence map›Paper›PMID 26121062›Full record

ArticleNano letters2015

Probing DNA Stiffness through Optical Fluctuation Analysis of Plasmon Rulers.

Tianhong Chen, Yan Hong, Björn M Reinhard

Abstract read
In one paragraph

Article in Nano letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Unraveling the binding microprocess of individualJournal of oral microbiology · 2022
    Article
  5. Article
  6. Review
  7. Plasmonic probing of the adhesion strength of single microbial cells.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. Review
  9. Recent Developments in Nanosensors for Imaging Applications in Biological Systems.Annual review of analytical chemistry (Palo Alto, Calif.) · 2019
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tianhong ChenDepartment of Chemistry and the Photonics Center, Boston University, Boston, Massachusetts 02215, United States.
Yan HongDepartment of Chemistry and the Photonics Center, Boston University, Boston, Massachusetts 02215, United States.
Björn M ReinhardDepartment of Chemistry and the Photonics Center, Boston University, Boston, Massachusetts 02215, United States.
Boston University · US

Funding

Illuminating Dynamic Receptor Clustering in the Epidermal Growth Factor Receptor Signal Transduction Pathway Using Plasmon CouplingR01CA138509 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Bjoern Markus Reinhard · 2009 to 2026
$5.9M
NCI NIH HHS R01 CA138509NCI NIH HHS R01CA138509
6 · The paper itself

Abstract

The distance-dependent plasmon coupling between biopolymer tethered gold or silver nanoparticles forms the foundation for the so-called plasmon rulers. While conventional plasmon ruler applications focus on the detection of singular events in the far-field spectrum, we perform in this Letter a ratiometric analysis of the continuous spectral fluctuations arising from thermal interparticle separation variations in plasmon rulers confined to fluid lipid membranes. We characterized plasmon rulers with different DNA tethers and demonstrate the ability to detect and quantify differences in the plasmon ruler potential and tether stiffness. The influence of the nature of the tether (single-stranded versus double-stranded DNA) and the length of the tether is analyzed. The characterization of the continuous variation of the interparticle separation in individual plasmon rulers through optical fluctuation analysis provides additional information about the conformational flexibility of the tether molecule(s) located in the confinement of the deeply subdiffraction limit interparticle gap and enhances the versatility of plasmon rulers as a tool in Biophysics and Nanotechnology.

Indexed as

DimerizationDNAElasticityGoldHardnessNanoparticlesSilverSurface Plasmon ResonanceDNAGoldSilverforce sensormolecular rulerNanoconfinementplasmon couplingplasmon hybridizationself-assembly

Identifiers

PMID26121062
PMCPMC4624404
OpenAlexW2312466583

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.