Evidence map›Paper›PMID 26120573›Full record

ArticleBritish microbiology research journal2014

Prevalence and Genotypic Characterization of Extended-Spectrum Beta-Lactamases Produced by Gram Negative Bacilli at a Tertiary Care Hospital in Rural South Western Uganda.

Acaku Moses, Freddie Bwanga, Yap Boum, Joel Bazira

Open access · bronzeAbstract read
In one paragraph

Article in British microbiology research journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. CTX-M, TEM, and SHV Genes inInfection and drug resistance · 2024
    Article
  6. Article
  7. Genetic Determinants of Resistance among ESBL-ProducingThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021
    Review
  8. Article
  9. Review
  10. Review
  11. Emerging Perils of Extended SpectrumBioMed research international · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Acaku MosesDepartment of Microbiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Freddie BwangaDepartment of Medical Microbiology, Makerere University College of Health sciences, Uganda ; MBN Clinical Laboratories Kampala, Uganda.
Yap BoumEpicenter Mbarara Research Base, Mbarara, Uganda.
Joel BaziraDepartment of Microbiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Mbarara University of Science and Technology · UGEpicentre Uganda · UG

Funding

Medical Education for Services to All Ugandans (MESAU)R24TW008886 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2010 to 2015
$9.2M
FIC NIH HHS R24 TW008886
6 · The paper itself

Abstract

aimTo determine the prevalence and genotypic characterisation of extended spectrum beta-lactamases produced by gram negative bacilli isolated at Mbarara Regional Referral Hospital (MRRH). SAMPLES: Gram negative clinical isolates. STUDY

designLaboratory-based descriptive cross-sectional study. PLACE AND DURATION OF THE STUDY: MRRH, June and August 2012.

methodsGram negative clinical isolates were sub cultured, and identified using biochemical tests. They were screened for ESBL by using oxyimino-cephalosporins and confirmed by double disc synergy Genotyping was performed using the PCR for TEM, SHV and CTX-M. Susceptibility pattern for the extended spectrum beta-lactamases, (ESBL) - positive isolates to other antibiotic classes was performed by the Kirby Bauer Technique.

resultsA total of 484 isolates were included in the study. The commonest ESBL producers were

conclusionESBL production among the Gram-negative clinical isolates at MRRH is very high with several isolates possessing multiple genes. The ESBL producers are highly susceptible to imipenem, but very resistant to ciprofloxacin.

Indexed as

AntibioticsESBLresistance patternssensitivity patternsUganda

Identifiers

PMID26120573
PMCPMC4479293
OpenAlexW2111167257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.