Evidence map›Paper›PMID 26120204›Full record

ArticleReports on progress in physics. Physical Society (Great Britain)2010

Diffuse Optics for Tissue Monitoring and Tomography.

T Durduran, R Choe, W B Baker, A G Yodh

Registry-linked trialAbstract read
In one paragraph

Article in Reports on progress in physics. Physical Society (Great Britain), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04767659 (Optical Monitoring of Neoadjuvant Chemotherapy and Prediction of Pathological Complete Response in Breast Cancer Patients), which is not on this map. Cited by 465 papers.

0numbers the graph read from it
0cells of the map it votes in
465citing papers in PubMed
25.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04767659 narecruitingnot on this mapstarted 2020, after this paper: background citation

Optical Monitoring of Neoadjuvant Chemotherapy and Prediction of Pathological Complete Response in Breast Cancer Patients

TypeinterventionalSponsorIRCCS San RaffaeleRan2020 to 2025Enrolled20ConditionsBreast Cancer Female, Chemotherapy EffectArmsMAMMOT2
3 · Its place in the literature

Who cites it

465 citing papers in PubMed, 1,152 citations in OpenAlex.

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405 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

T DurduranICFO- Institut de Ciències Fotòniques, Mediterranean Technology Park, 08860 Castelldefels (Barcelona), Spain.
R ChoeDepartment of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA.
W B BakerDepartment of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA.
A G YodhDepartment of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA.
University of Pennsylvania · USInstitute of Photonic Sciences · ES

Funding

WORKSHOP ON ADVANCES IN MUSCULOSKELETAL MRIP41RR002305 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI SONG, HEE KWON · 1985 to 2011
$14.7M
statistics coreP30NS045839 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DETRE, JOHN A · 2003 to 2017
$10.1M
Diffuse Optics for Acute Stroke ManagementR01NS060653 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI YODH, ARJUN G. · 2008 to 2018
$5.5M
NINR Intramural Research Training ProgramsZ01NR000016 · NINR · NATIONAL INSTITUTE OF NURSING RESEARCH · PI DIONNE, RAYMOND · 2007 to 2008
$1.6M
In Vivo Cancer Therapy Monitoring with Diffuse Optical MethodsR00CA126187 · NCI · UNIVERSITY OF ROCHESTER · PI CHOE, REGINE · 2011 to 2013
$710k
FLOW IN THICK TISSUES PROBED BY DIFFUSING LIGHTR01HL057835 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI YODH, ARJUN G. · 1997 to 2001
$489k
Absolute Measurement of Cerebral Blood Flow Using Diffuse OpticsR21EB007610 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI DURDURAN, TURGUT · 2007 to 2008
$413k
In Vivo Cancer Therapy Monitoring with Diffuse Optical MethodsK99CA126187 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHOE, REGINE · 2008 to 2009
$164k
Intramural NIH HHS Z01 NR000016NCI NIH HHS K99 CA126187NCI NIH HHS R00 CA126187NCRR NIH HHS P41 RR002305NHLBI NIH HHS R01 HL057835NIBIB NIH HHS R21 EB007610NINDS NIH HHS P30 NS045839NINDS NIH HHS R01 NS060653
6 · The paper itself

Abstract

This review describes the diffusion model for light transport in tissues and the medical applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue hemodynamics, wherein quantitative assessment of oxy- and deoxy-hemoglobin concentrations and blood flow are desired. The theoretical basis for near-infrared or diffuse optical spectroscopy (NIRS or DOS, respectively) is developed, and the basic elements of diffuse optical tomography (DOT) are outlined. We also discuss diffuse correlation spectroscopy (DCS), a technique whereby temporal correlation functions of diffusing light are transported through tissue and are used to measure blood flow. Essential instrumentation is described, and representative brain and breast functional imaging and monitoring results illustrate the workings of these new tissue diagnostics.

Identifiers

PMID26120204
PMCPMC4482362
OpenAlexW2061135416

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.