Evidence map›Paper›PMID 26120162›Full record

ArticleIndian journal of dermatology

Lesch-Nyhan Syndrome in an Indian Child.

Priyanka Chandekar, Bhushan Madke, Sumit Kar, Nidhi Yadav

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Priyanka ChandekarDepartment of Dermatology, Venereology and Leprosy, Mahatma Gandhi Institute of Medical Sciences and Kasturba Hospital, Sewagram, Wardha, Maharashtra, India.
Bhushan MadkeDepartment of Dermatology, Venereology and Leprosy, Mahatma Gandhi Institute of Medical Sciences and Kasturba Hospital, Sewagram, Wardha, Maharashtra, India.
Sumit KarDepartment of Dermatology, Venereology and Leprosy, Mahatma Gandhi Institute of Medical Sciences and Kasturba Hospital, Sewagram, Wardha, Maharashtra, India.
Nidhi YadavDepartment of Dermatology, Venereology and Leprosy, Mahatma Gandhi Institute of Medical Sciences and Kasturba Hospital, Sewagram, Wardha, Maharashtra, India.
Kasturba Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxanthine guanine phosphoribosyl transferase-1 (HGPRT-1) leading to Lesch-Nyhan syndrome (LNS) is one of the important causes of self-mutilation. Hereby, we report a case of LNS in a three and half-year-old male child, who presented with characteristic self-mutilating behavior. He had history of developmental delay, difficulty in social interaction, attention deficit and features of autism. His serum blood biochemistry was normal except for low hemoglobin levels and raised serum uric acid levels. With a diagnosis of LNS, the child was treated with allopurinol. With various modalities of physical restraint, his self-mutilating behavior came under control and currently the patient is being followed up.

Indexed as

hyperuricemiaHypoxanthine guanine phosphoribosyl transferase deficiencyLesch-Nyhan syndromeself-mutilationuric acid metabolism.

Identifiers

PMID26120162
PMCPMC4458947
OpenAlexW1540107705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.