Evidence map›Paper›PMID 26120074›Full record

ReviewCNS spectrums2015

Error-processing abnormalities in pediatric anxiety and obsessive compulsive disorders.

Kate D Fitzgerald, Stephan F Taylor

Abstract readReview
In one paragraph

Review in CNS spectrums, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Mechanisms of Change in Exposure Therapy for Anxiety and Related Disorders: A Research Agenda.Clinical psychological science : a journal of the Association for Psychological Science · 2025
    Article
  4. Article
  5. The gray matter morphology associated with the electrophysiological response to errors in individuals with high trait anxiety.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2023
    Article
  6. Defining brain-based OCD patient profiles using task-based fMRI and unsupervised machine learning.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  7. Review
  8. Review
  9. The prefrontal cortex and OCD.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Development of Posterior Medial Frontal Cortex Function in Pediatric Obsessive-Compulsive Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2018
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kate D Fitzgerald
Stephan F Taylor

Funding

Neurocircuit mechanisms of OCD across the lifespanR01MH102242 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FITZGERALD, KATE DIMOND, TAYLOR, STEPHAN F · 2014 to 2018
$3.3M
fMRI study of developing medial prefrontal cortical function in pediatric OCDK23MH082176 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FITZGERALD, KATE DIMOND · 2008 to 2012
$899k
NIMH NIH HHS K23 MH082176NIMH NIH HHS R01 MH102242
6 · The paper itself

Abstract

Anxiety and obsessive compulsive disorders are among the earliest occurring psychopathology and may derive from atypical maturation of neural networks for error processing. Psychological models have alternately suggested that over-detection of errors, excessive caring about errors, or failure of errors to elicit regulatory control could associate with the expression of anxiety. In this review article, the potential relevance of error processing for anxiety and obsessive compulsive disorders is described in the context of neurophysiological and functional magnetic resonance imaging (fMRI) research demonstrating altered brain response to errors in pediatric and adult patients. Finally, hypotheses about developmentally sensitive mechanisms of anxiety and obsessive compulsive disorders are drawn from the extant literature, and avenues for clinical translation are discussed.

Indexed as

ConnectomeAdolescentAnxietyBrainChildHumansMagnetic Resonance ImagingObsessive-Compulsive Disorder

Identifiers

PMID26120074
PMCPMC4929060

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.