SynthesisWorld journal of urology2016
Meta-analysis of metabolic syndrome and benign prostatic hyperplasia in Chinese patients.
Synthesis in World journal of urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- The Association Between Metabolic Syndrome and Characteristics of Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis.Medicine · 2016Pooled it
- The gut-prostate axis in benign prostatic diseases: Mechanistic pathways and therapeutic implications.iScience · 2026Review
- Prevalence and association of metabolic syndrome components with benign prostate hyperplasia.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Risk factors for benign prostatic hyperplasia: a comprehensive review.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Awareness and prevalence of self-reported benign prostatic hyperplasia: a cross-sectional study in Saudi Arabia.Frontiers in public health · 2024Article
- The Relationship Between Metabolic Syndrome and Benign Prostate Enlargement: A Case-Control Study in a Peruvian Military Hospital.Urology research & practice · 2023Article
- Icariin ameliorates metabolic syndrome-induced benign prostatic hyperplasia in rats.Environmental science and pollution research international · 2022Article
- Triglyceride to high-density lipoprotein cholesterol ratio and total cholesterol to high-density lipoprotein cholesterol ratio and risk of benign prostatic hyperplasia in Chinese male subjects.Frontiers in nutrition · 2022Article
- Metabolic syndrome is associated with prostate enlargement: a systematic review, meta-analysis, and meta-regression on patients with lower urinary tract symptom factors.Therapeutic advances in endocrinology and metabolism · 2021Article
- Thiol Groups as a Biomarker for the Diagnosis and Prognosis of Prostate Cancer.Scientific reports · 2020Article
- Topic issue: men's health in 2019.World journal of urology · 2019Article
- Effects of metformin on prostatic tissue of rats with metabolic syndrome and benign prostatic hyperplasia.International urology and nephrology · 2018Article
- Clear pooled results but unclear pooled bias: commentary for a recent meta-analysis.World journal of urology · 2017Article
- Metabolic syndrome and benign prostatic hyperplasia: An update.Asian journal of urology · 2017Review
- Obesity as a Risk Factor for Prostatic Enlargement: A Retrospective Cohort Study in Korea.International neurourology journal · 2016Article
- Associations between metabolic syndrome and clinical benign prostatic hyperplasia in a northern urban Han Chinese population: A prospective cohort study.Scientific reports · 2016Article
- Correlations of Metabolic Components with Prostate Volume in Middle-Aged Men Receiving Health Check-Up.PloS one · 2016Article
- Preliminary assessment of Neck Circumference in Benign Prostatic Hyperplasia in Patients with Metabolic Syndrome.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- Re: Preliminary assessment of neck circumference in benign prostatic hyperplasia in patients with metabolic syndrome.International braz j urol : official journal of the Brazilian Society of UrologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the impact of metabolic syndrome (MetS) on benign prostatic hyperplasia (BPH), focusing on MetS and its relationship with prostate volume and prostate-specific antigen (PSA) in Chinese patients by performing a meta-analysis.
methodsWe systematically searched the PubMed, Embase, China National Knowledge Infrastructure, Wanfang, and VIP databases from inception to November 2014. All studies investigating the impact of MetS on prostate volume and PSA among BPH patients were included. Pooled mean difference (WMD) and 95% confidence interval (CI) were used to analyze the difference between patients with MetS and those without MetS.
resultsSixteen studies enrolled 1895 BPH patients, of whom 2224 had MetS. Compared with those without MetS, BHP patients with MetS had significantly higher total prostate volume (WMD 10.15 ml; 95% CI 7.37-12.93) and serum PSA level (WMD 0.53 ng/ml; 95% CI 0.17-0.88), respectively. In addition, annual prostate growth rate in patients with MetS was higher (WMD 0.49 ml/year; 95% CI 0.24-0.73) than in those without MetS.
conclusionsThis meta-analysis supports that the presence of MetS increases total prostate volume and annual prostate growth rate in Chinese BPH patients. Future studies are needed to explain the detailed underlying mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.