ArticleScientific reports2015
Investigation of multipotent postnatal stem cells from human maxillary sinus membrane.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Regenerative potential of Schneiderian membrane-derived mesenchymal stem cells in sinus floor elevation model and calvarial defect model.Journal of Zhejiang University. Science. B · 2026Article
- Emerging Biomaterials for Maxillary Sinus Augmentation: From In Vitro Insights to In Vivo Clinical Translation.Materials (Basel, Switzerland) · 2026Review
- Human Periodontal Ligament Stem Cells (hPDLSCs) Spontaneously Differentiate into Myofibroblasts to Repair Diabetic Wounds.Bioengineering (Basel, Switzerland) · 2024Article
- Transcriptome analysis of osteogenic differentiation of human maxillary sinus mesenchymal stem cells using RNA-Seq.Heliyon · 2023Article
- Effects of G-CSF on hPDLSC proliferation and osteogenic differentiation in the LPS-induced inflammatory microenvironment.BMC oral health · 2023Article
- The impact of polydeoxyribonucleotide on early bone formation in lateral-window sinus floor elevation with simultaneous implant placement.Journal of periodontal & implant science · 2023Article
- Article
- Effects of platelet-rich fibrin on osteogenic differentiation of Schneiderian membrane derived mesenchymal stem cells and bone formation in maxillary sinus.Cell communication and signaling : CCS · 2022Article
- Effectiveness of hydraulic pressure-assisted sinus augmentation in a rabbit sinus model: a preclinical study.Clinical oral investigations · 2022Article
- Influence of anatomical factors related to maxillary sinus on outcomes of transcrestal sinus floor elevation.Journal of dental sciences · 2022Article
- Tracking of Oral and Craniofacial Stem Cells in Tissue Development, Regeneration, and Diseases.Current osteoporosis reports · 2021Review
- Roles of mitochondrial unfolded protein response in mammalian stem cells.World journal of stem cells · 2021Review
- Influence of implant protrusion length on non-grafting osteotome sinus floor elevation with simultaneous implant: a 3- to 9-year retrospective study.International journal of implant dentistry · 2021Article
- Promoting effect of rapamycin on osteogenic differentiation of maxillary sinus membrane stem cells.PeerJ · 2021Article
- Conventional and Emerging Markers in Stem Cell Isolation and Characterization.Advances in experimental medicine and biology · 2021Review
- Long Noncoding RNA Expression Profiles of Periodontal Ligament Stem Cells from the Periodontitis Microenvironment in Response to Static Mechanical Strain.Stem cells international · 2021Article
- Osteogenic differentiation and inflammatory response of recombinant human bone morphogenetic protein-2 in human maxillary sinus membrane-derived cells.Experimental and therapeutic medicine · 2020Article
- Evaluation of the adhesion of human dental pulp stem cells to different endodontic biomaterials before and after setting.Journal of dental research, dental clinics, dental prospects · 2020Article
- Characterization of Different Sources of Human MSCs Expanded in Serum-Free Conditions with Quantification of Chondrogenic Induction in 3D.Stem cells international · 2019Article
- Head to Knee: Cranial Neural Crest-Derived Cells as Promising Candidates for Human Cartilage Repair.Stem cells international · 2019Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maxillary sinus membrane (MSM) elevation is a common surgical technique for increasing bone height in the posterior maxilla prior to dental implant placement. However, the biological nature of bone regeneration in MSM remains largely unidentified. In this study, MSM tissue was obtained from 16 individuals during orthognathic surgery and used to isolate MSM stem cells (MSMSCs) by single-colony selection and STRO-1 cell sorting. The cell characteristics in terms of colony-forming ability, cell surface antigens, multi-differentiation potential and in vivo implantation were all evaluated. It was found that MSMSCs were of mesenchymal origin and positive for mesenchymal stem cell (MSC) markers such as STRO-1, CD146, CD29 and CD44; furthermore, under defined culture conditions, MSMSCs were able to form mineral deposits and differentiate into adipocytes and chondrocytes. When transplanted into immunocompromised rodents, MSMSCs showed the capacity to generate bone-like tissue and, importantly, maintain their MSC characteristics after in vivo implantation. These findings provide cellular and molecular evidence that MSM contains stem cells that show functional potential in bone regeneration for dental implant.
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Registered trials
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