Evidence map›Paper›PMID 26119199›Full record

ArticleInfection2016

Clinical and microbiological features of infective endocarditis caused by aerococci.

Torgny Sunnerhagen, Bo Nilson, Lars Olaison, Magnus Rasmussen

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. An unusual case ofIDCases · 2026
    Article
  4. Article
  5. Observational
  6. Article
  7. IDCases · 2024
    Article
  8. Emerging pathogensFuture microbiology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Oral Therapy forFederal practitioner : for the health care professionals of the VA, DoD, and PHS · 2022
    Article
  15. Clinical and microbiological characterization of Aerococcus urinae bacteraemias at Helsinki metropolitan area, Finland.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  16. Article
  17. Article
  18. Journal of medical cases · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Torgny SunnerhagenDivision of Infection Medicine, Department of Clinical Sciences, Lund University, Tornavägen 10, BMC B14, 221 84, Lund, Sweden.
Bo NilsonClinical Microbiology, Labmedicin, Region Skåne, Lund, Sweden.
Lars OlaisonDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Magnus RasmussenDivision of Infection Medicine, Department of Clinical Sciences, Lund University, Tornavägen 10, BMC B14, 221 84, Lund, Sweden. magnus.rasmussen@med.lu.se.
Lund University · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo define the clinical presentation of aerococcal infective endocarditis (IE) and the prevalence of synergy between penicillin and gentamicin on aerococcal isolates.

methodsCases of aerococcal IE between 2002 and 2014 were identified in the Swedish Registry of Infective Endocarditis (SRIE). MALDI-TOF MS was used to confirm species determination. The medical records were analysed and compared to cases reported to the SRIE caused by other pathogens.

resultsSixteen cases of aerococcal IE, fourteen with Aerococcus urinae and two with Aerococcus sanguinicola, were confirmed. Etest-based methods and time-kill experiments suggested synergy between penicillin and gentamicin towards seven of fifteen isolates. The patients with aerococcal IE were significantly older than those with streptococci or Staphylococcus aureus IE. Most of the patients had underlying urinary tract diseases or symptoms suggesting a urinary tract focus of the infection. Seven patients with aerococcal IE presented with severe sepsis but ICU treatment was needed only in one patient and there was no fatality. Valve exchange surgery was needed in four patients and embolization was seen in three patients.

conclusionsThis report is the largest on aerococcal IE and suggests that the prognosis is relatively favourable despite the fact that the patients are old and have significant comorbidities.

Indexed as

AerococcusAgedAged, 80 and overAnti-Bacterial AgentsDisk Diffusion Antimicrobial TestsDrug SynergismEndocarditisFemaleGentamicinsGram-Positive Bacterial InfectionsHumansMaleMiddle AgedPenicillinsPrognosisSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAnti-Bacterial AgentsGentamicinsPenicillinsAerococcusAerococcus sanguinicolaAerococcus urinaeInfective endocarditisPrognosisSynergy

Identifiers

PMID26119199
OpenAlexW1815074416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.