Evidence map›Paper›PMID 26118562›Full record

ArticleSleep2015

Insufficient Sleep and Risk of Prostate Cancer in a Large Swedish Cohort.

Sarah C Markt, Alessandra Grotta, Olof Nyren, Hans-Olov Adami, Lorelei A Mucci, Unnur A Valdimarsdottir, Pär Stattin, Rino Bellocco, Ylva Trolle Lagerros

Abstract read
In one paragraph

Article in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The Relationship between Circadian Rhythm and Cancer Disease.International journal of molecular sciences · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Sleep duration as an independent factor associated with vitamin D levels in the EPISONO cohort.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah C MarktDepartment of Epidemiology, Harvard School of Public Health, Boston, MA.
Alessandra GrottaDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Olof NyrenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Hans-Olov AdamiDepartment of Epidemiology, Harvard School of Public Health, Boston, MA.
Lorelei A MucciDepartment of Epidemiology, Harvard School of Public Health, Boston, MA.
Unnur A ValdimarsdottirDepartment of Epidemiology, Harvard School of Public Health, Boston, MA.
Pär StattinSurgery and Perioperative Sciences, Urology and Andrology, Umeå University Hospital, Umeå, Sweden.
Rino BelloccoDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Ylva Trolle LagerrosUnit of Clinical Epidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Funding

Training Program in Cancer EpidemiologyT32CA009001 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI A. Heather Eliassen, Meir Stampfer · 1985 to 2026
$17.3M
NCI NIH HHS T32 CA009001NCI NIH HHS T32 CA09001
6 · The paper itself

Abstract

STUDY

objectiveThere are some data to suggest that insufficient sleep, including short sleep duration and sleep disruption, may be associated with an increased risk of cancer. We investigated the association between sleep duration and sleep disruption and risk of prostate cancer.

designProspective cohort study.

settingSweden.

participantsA total of 14,041 men in the Swedish National March Cohort.

interventionsNone. MEASUREMENTS AND

resultsHabitual sleep duration and sleep disruption were self-reported in 1997. Prostate cancer diagnoses, including lethal (metastases at diagnosis or death from prostate cancer) and advanced (stage T4, N1, or M1 at diagnosis or death from prostate cancer), were determined from linkage to nationwide cancer registries through 2010. We conducted Cox proportional hazards regression adjusted for potential confounding variables. During 13 years of follow-up, we identified 785 cases of incident prostate cancer, including 118 lethal and 127 advanced cases. Four percent of men reported sleeping 5 h or less a night, and 2% reported sleeping 9 h or more per night. We found no association between sleep duration and risk of prostate cancer overall or for advanced/lethal disease. We also did not find an association between prostate cancer and sleep disruption, as defined by difficulty falling asleep, difficulty maintaining sleep, sleep quality, and restorative power of sleep.

conclusionsIn this large prospective study from Sweden, we found no association between habitual sleep duration or sleep disruption and risk of prostate cancer.

Indexed as

Cohort StudiesHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesProstatic NeoplasmsRiskSelf ReportSleepSleep DeprivationSleep Initiation and Maintenance DisordersSwedenTime Factorsprostate cancersleep disruptionsleep duration

Identifiers

PMID26118562
PMCPMC4531408

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.