Trial reportSleep2015
An Economic Evaluation of Home Versus Laboratory-Based Diagnosis of Obstructive Sleep Apnea.
Trial report in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00642486 (Portable Monitoring in the Diagnosis and Management of Obstructive Sleep Apnea), which is not on this map. Cited by 59 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Portable Monitoring in the Diagnosis and Management of Obstructive Sleep Apnea
Who cites it
59 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Home-testing devices for diagnosing obstructive sleep apnoea hypopnoea syndrome - a systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2026Pooled it
- Clinical utility of limited channel sleep studies versus polysomnography for obstructive sleep apnoea.The Cochrane database of systematic reviews · 2025Pooled it
- Content Comparison of Quality-of-Life Instruments Used in Economic Evaluations of Sleep Disorder Interventions: A Systematic Review.PharmacoEconomics · 2024Pooled it
- Validation of the STOP-Bang questionnaire as a screening tool for obstructive sleep apnoea in patients with cardiovascular risk factors: a systematic review and meta-analysis.BMJ open respiratory research · 2021Pooled it
- Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017Guideline
- Trial
- Long-term night-to-night variability of sleep-disordered breathing using a radar-based home sleep apnea test: a prospective cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Trial
- Initiation of therapy for obstructive sleep apnea syndrome: a randomized comparison of outcomes of telemetry-supported home-based vs. sleep lab-based therapy initiation.Sleep & breathing = Schlaf & Atmung · 2022Trial
- A randomized controlled trial of an ambulatory approach versus the hospital-based approach in managing suspected obstructive sleep apnea syndrome.Scientific reports · 2017Trial
- A novel approach using actigraphy to quantify the level of disruption of sleep by in-home polysomnography: the MrOS Sleep Study: Sleep disruption by polysomnography.Sleep medicine · 2017Trial
- Evaluation of apap parameters in one to three nights titration for final pressure decision-making in a real world clinical setting.Sleep & breathing = Schlaf & Atmung · 2026Article
- AI-Driven Sleep Staging Using Instantaneous Heart Rate and Accelerometry: Insights From an Apple Watch Study.IEEE transactions on bio-medical engineering · 2026Article
- Article
- Feasibility, Validity and Economic Impact of a Home-Based Sleep Screening Test in the Detection of Sleep-Related Breathing Disorders in Individuals Living With Spinal Cord Injury: A Multi-Method Study and Cost-Minimisation Analysis.Journal of sleep research · 2026Article
- OSA screening before CGRP mAbs in chronic migraine.Sleep & breathing = Schlaf & Atmung · 2026Review
- The Global Socioeconomic Burden of Obstructive Sleep Apnea: A Comprehensive Review.Healthcare (Basel, Switzerland) · 2025Review
- Home Sleep Apnoea Testing: Advances, Challenges and Considerations in Heart Failure.Cardiac failure review · 2025Review
- Remote Titration of Mandibular Advancement Devices: What Outcomes Should We Target?Annals of the American Thoracic Society · 2024Article
- The OSA patient journey: pathways for diagnosis and treatment among commercially insured individuals in the United States.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Risk factors for collisions attributed to microsleep-related behaviors while driving in professional truck drivers.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesWe conducted an economic analysis of the HomePAP study, a multicenter randomized clinical trial that compared home-based versus laboratory-based testing for the diagnosis and management of obstructive sleep apnea (OSA).
designA cost-minimization analysis from the payer and provider perspectives was performed, given that 3-mo clinical outcomes were equivalent.
settingSeven academic sleep centers.
participantsThere were 373 subjects at high risk for moderate to severe OSA.
interventionsSubjects were randomized to either home-based limited channel portable monitoring followed by unattended autotitration with continuous positive airway pressure (CPAP), versus a traditional pathway of in-laboratory sleep study and CPAP titration. MEASUREMENTS AND
resultsFrom the payer perspective, per subject costs for the laboratory-based pathway were $1,840 (95% confidence interval [CI] $1,660, $2,015) compared to $1,575 (95% CI $1,439, $1,716) for the home-based pathway under the base case. Costs were $264 (95% CI $39, $496, P = 0.02) in favor of the home arm. From the provider perspective, per subject costs for the laboratory arm were $1,697 (95% CI $1,566, $1,826) compared to $1,736 (95% CI $1,621, $1,857) in the home arm, for a difference of $40 (95% CI -$213, $142, P = 0.66) in favor of the laboratory arm under the base case. The provider operating margin was $142 (95% CI $85, $202,P < 0.01) in the laboratory arm, compared to a loss of -$161 (95% CI -$202, -$120, P < 0.01) in the home arm.
conclusionsFor payers, a home-based diagnostic pathway for obstructive sleep apnea with robust patient support incurs fewer costs than a laboratory-based pathway. For providers, costs are comparable if not higher, resulting in a negative operating margin. CLINICALTRIALSGOV IDENTIFIER: NCT00642486.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.