ReviewBriefings in functional genomics2016
The past, present and future of mitochondrial genomics: have we sequenced enough mtDNAs?
Review in Briefings in functional genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
73 citing papers in PubMed.
- Review
- Navigating Cetacean Mitochondrial Genome Data: Identifying Coverage and Deficiencies in Public Repositories.Molecular ecology resources · 2026Article
- Phylogenetic Relationships of Five Phallales Species Based on Mitochondrial Genome Analysis.Journal of fungi (Basel, Switzerland) · 2026Article
- From Rigid Order to Radical Variation: Mitogenome Evolution in the Main Lineages of a Lesser-Known Animal Phylum (Gastrotricha).Genome biology and evolution · 2026Article
- Characteristics and Phylogenetic Considerations of the Newly Sequenced Mitochondrial Genome ofBiology · 2026Article
- The Complete Mitochondrial Genome of theBiology · 2026Article
- Complete mitochondrial genomic sequence ofMitochondrial DNA. Part B, Resources · 2026Article
- Article
- The complete mitochondrial genomes of the two species of Astyanax (Characiformes: Acestrorhamphidae) that occur in cenotes of the Yucatán Peninsula karst aquifer: comparative analyses and their taxonomic implications.Molecular biology reports · 2025Article
- Mitochondrial Genome Variations and Possible Adaptive Implications in Some Tephritid Flies (Diptera, Tephritidae).International journal of molecular sciences · 2025Article
- Complete mitochondrial genome of the ectomycorrhizal fungusMitochondrial DNA. Part B, Resources · 2025Article
- Mitochondrial Genomes of Mammals from the Brazilian Cerrado and Phylogenetic Considerations for the Orders Artiodactyla, Carnivora, and Chiroptera (Chordata: Mammalia).Life (Basel, Switzerland) · 2024Article
- Connecting Species-Specific Extents of Genome Reduction in Mitochondria and Plastids.Molecular biology and evolution · 2024Article
- Characterization and analysis of multi-organ full-length transcriptomes in Sphaeropteris brunoniana and Alsophila latebrosa highlight secondary metabolism and chloroplast RNA editing pattern of tree ferns.BMC plant biology · 2024Article
- The first complete mitochondrional genome ofF1000Research · 2024Article
- A Customized Human Mitochondrial DNA Database (hMITO DB v1.0) for Rapid Sequence Analysis, Haplotyping and Geo-Mapping.International journal of molecular sciences · 2023Article
- Phylogenomic resolution of Imparidentia (Mollusca: Bivalvia) diversification through mitochondrial genomes.Marine life science & technology · 2023Article
- Highly-multiplexed and efficient long-amplicon PacBio and Nanopore sequencing of hundreds of full mitochondrial genomes.BMC genomics · 2023Article
- Article
- Comparative Analysis of Mitochondrial Genomes in Two Subspecies of the Sunwatcher Toad-Headed Agama (Genes · 2022Article
13 more citing papers are in PubMed but not listed here.
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1 author.
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No grant is acknowledged in the PubMed record.
Abstract
The year 2014 saw more than a thousand new mitochondrial genome sequences deposited in GenBank-an almost 15% increase from the previous year. Hundreds of peer-reviewed articles accompanied these genomes, making mitochondrial DNAs (mtDNAs) the most sequenced and reported type of eukaryotic chromosome. These mtDNA data have advanced a wide range of scientific fields, from forensics to anthropology to medicine to molecular evolution. But for many biological lineages, mtDNAs are so well sampled that newly published genomes are arguably no longer contributing significantly to the progression of science, and in some cases they are tying up valuable resources, particularly journal editors and referees. Is it time to acknowledge that as a research community we have published enough mitochondrial genome papers? Here, I address this question, exploring the history, milestones and impacts of mitochondrial genomics, the benefits and drawbacks of continuing to publish mtDNAs at a high rate and what the future may hold for such an important and popular genetic marker. I highlight groups for which mtDNAs are still poorly sampled, thus meriting further investigation, and recommend that more energy be spent characterizing aspects of mitochondrial genomes apart from the DNA sequence, such as their chromosomal and transcriptional architectures. Ultimately, one should be mindful before writing a mitochondrial genome paper. Consider perhaps sending the sequence directly to GenBank instead, and be sure to annotate it correctly before submission.
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