ArticleJournal of experimental botany2015
Auxin-driven patterning with unidirectional fluxes.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 62 citations in OpenAlex.
- Reticulate leaf venation in Pilea peperomioides is a Voronoi diagram.Nature communications · 2026Article
- A BRC1-modulated switch in auxin efflux accounts for the competition between Arabidopsis axillary buds.PLoS biology · 2025Article
- Modeling Arabidopsis root growth and development.Plant physiology · 2025Review
- The role of auxin transport through plasmodesmata in leaf vein canalization and patterning.Frontiers in plant science · 2025Article
- The Effects of Auxin Transport Inhibition on the Formation of Various Leaf and Vein Patterns.Plants (Basel, Switzerland) · 2024Article
- Developmental timing in plants.Nature communications · 2024Review
- Regulation of tissue growth in plants - A mathematical modeling study on shade avoidance response inFrontiers in plant science · 2024Article
- Computer models of cell polarity establishment in plants.Plant physiology · 2023Review
- PIN-FORMED1 polarity in the plant shoot epidermis is insensitive to the polarity of neighboring cells.iScience · 2022Article
- Developmental regulation of leaf venation patterns: monocot versus eudicots and the role of auxin.The New phytologist · 2022Review
- Computational Models of Auxin-Driven Patterning in Shoots.Cold Spring Harbor perspectives in biology · 2022Review
- Article
- A Molecular Pinball Machine of the Plasma Membrane Regulates Plant Growth-A New Paradigm.Cells · 2021Review
- What remains of the evidence for auxin feedback on PIN polarity patterns?Plant physiology · 2021Article
- Of Cells, Strands, and Networks: Auxin and the Patterned Formation of the Vascular System.Cold Spring Harbor perspectives in biology · 2021Review
- Shaping the Organ: A Biologist Guide to Quantitative Models of Plant Morphogenesis.Frontiers in plant science · 2021Review
- Integration of Core Mechanisms Underlying Plant Aerial Architecture.Frontiers in plant science · 2021Review
- Auxin canalization and vascular tissue formation by TIR1/AFB-mediated auxin signaling in Arabidopsis.The New phytologist · 2020Article
- Mathematical Modelling of Auxin Transport in Plant Tissues: Flux Meets Signalling and Growth.Bulletin of mathematical biology · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plant hormone auxin plays an essential role in the patterning of plant structures. Biological hypotheses supported by computational models suggest that auxin may fulfil this role by regulating its own transport, but the plausibility of previously proposed models has been questioned. We applied the notion of unidirectional fluxes and the formalism of Petri nets to show that the key modes of auxin-driven patterning-the formation of convergence points and the formation of canals-can be implemented by biochemically plausible networks, with the fluxes measured by dedicated tally molecules or by efflux and influx carriers themselves. Common elements of these networks include a positive feedback of auxin efflux on the allocation of membrane-bound auxin efflux carriers (PIN proteins), and a modulation of this allocation by auxin in the extracellular space. Auxin concentration in the extracellular space is the only information exchanged by the cells. Canalization patterns are produced when auxin efflux and influx act antagonistically: an increase in auxin influx or concentration in the extracellular space decreases the abundance of efflux carriers in the adjacent segment of the membrane. In contrast, convergence points emerge in networks in which auxin efflux and influx act synergistically. A change in a single reaction rate may result in a dynamic switch between these modes, suggesting plausible molecular implementations of coordinated patterning of organ initials and vascular strands predicted by the dual polarization theory.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.