Evidence map›Paper›PMID 26116729›Full record

ArticleThe Journal of infectious diseases2015

Varicella Zoster Virus in Temporal Arteries of Patients With Giant Cell Arteritis.

Don Gilden, Maria Nagel

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Polymyalgia Rheumatica After Herpes-Zoster.Archives of rheumatology · 2018
    Article
  10. Review
  11. Varicella Zoster Virus and Giant Cell Arteritis.The Journal of infectious diseases · 2016
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Don GildenDepartment of Neurology Department of Microbiology and Immunology, University of Colorado School of Medicine, Aurora.
Maria NagelDepartment of Neurology.
University of Colorado Denver · US

Funding

VARICELLA ZOSTER VIRUS VASCULOPATHY: CHANGING CLINICAL PRACTICEP01AG032958 · NIA · UNIVERSITY OF COLORADO DENVER · PI COHRS, RANDALL J. · 2009 to 2023
$30.3M
NIA NIH HHS AG032958NIA NIH HHS P01 AG032958
6 · The paper itself

Abstract

Giant cell arteritis (GCA) is an immune-mediated disease of unknown etiology. Varicella zoster virus (VZV) antigen was found in all of 4 GCA-positive temporal arteries (TAs) but was not present in any of 13 normal TAs. All 4 GCA-positive TAs contained viral antigen in skip areas, mostly in the adventitia and media and least in the intima. Despite formalin fixation, VZV DNA was detected in 2 of 4 GCA-positive, VZV antigen-positive TAs. Skeletal muscle was attached to 3 of 4 TAs, and VZV antigen was found in 2 and VZV DNA in 1. VZV may cause GCA.

Indexed as

Antibodies, ViralAntigens, ViralGiant Cell ArteritisHerpesvirus 3, HumanHistocytochemistryHumansMiddle AgedTemporal ArteriesAntibodies, ViralAntigens, Viralgiant cell arteritistemporal arteryvaricella zoster virus

Identifiers

PMID26116729
PMCPMC4574553
OpenAlexW2266829255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.