ArticleJournal of feline medicine and surgery2016
Feline non-regenerative immune-mediated anaemia: features and outcome in 15 cases.
Article in Journal of feline medicine and surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- Clinical Findings, Treatment and Long-Term Outcome in 37 Cats with Non-Associative Immune-Mediated Hemolytic Anemia: A Retrospective Observational Study of Two Treatment Cohorts.Animals : an open access journal from MDPI · 2026Article
- Feline leukaemia virus (FeLV) infection in domestic pet cats in Australia and New Zealand: Guidelines for diagnosis, prevention and management.Australian veterinary journal · 2025Review
- Prevalence of ocular lesions in cats with anaemia and thrombocytopenia.Journal of feline medicine and surgery · 2025Article
- Pure red cell aplasia and amegakaryocytic thrombocytopenia in a cat.The Journal of veterinary medical science · 2025Article
- Immune-Mediated Hemolytic Anemia in Cats with Feline Infectious Peritonitis.Pathogens (Basel, Switzerland) · 2025Article
- Clinical findings, treatment and outcome in cats diagnosed with precursor-targeted immune-mediated anaemia in a referral hospital in the UK: 30 cases (2010-2021).Veterinary record open · 2023Article
- 2022 Update of the Consensus on the Rational Use of Antithrombotics and Thrombolytics in Veterinary Critical Care (CURATIVE) Domain 1- Defining populations at risk.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2022Article
- Cyclosporine Treatment in Cats with Presumed Chronic Pancreatitis-A Retrospective Study.Animals : an open access journal from MDPI · 2021Article
- Presumptive precursor-targeted immune-mediated anemia concurrent with gastrointestinal lymphoma in a cat.The Journal of veterinary medical science · 2020Article
- Feline non-regenerative anemia: Diagnostic and treatment recommendations.Journal of feline medicine and surgery · 2019Article
- Ciclosporin and the cat: Current understanding and review of clinical use.Journal of feline medicine and surgery · 2018Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPure red cell aplasia (PRCA) and non-regenerative immune-mediated haemolytic anaemia (NRIMHA) are uncommon causes of non-regenerative anaemia affecting the bone marrow in the cat. This retrospective study aimed to describe the clinical features, treatment and outcome (remission and survival) of cats with these disorders.
methodsCases of PRCA and NRIMHA presenting between 2009 and 2013 were retrieved. Clinical features including signalment, history, clinical signs and diagnostic investigations were recorded, as well as treatment(s) used and outcome (remission and survival). Outcome was compared for PRCA and NRIMHA.
resultsFifteen cats met inclusion criteria: seven with PRCA and eight with NRIMHA. The majority (12/15) were younger than 3 years of age. Volume overload was common (8/11). Treatment with whole blood transfusions with or without Oxyglobin was necessary in most cats (14/15) and resulted in congestive heart failure in one cat. Most cats (11/15) achieved remission 12-42 days after starting immunosuppressive treatment. Treatment protocols associated with remission were glucocorticoids alone (remission in 6/7 cats), glucocorticoids and chlorambucil (remission in 3/6 treated cats), glucocorticoids and ciclosporin (one cat only) and ciclosporin alone (one cat only). Relapse was observed in 3/11 cats, and 8/11 cats were still receiving treatment at the time of follow-up. Outcome (remission and survival) did not differ between PRCA and NRIMHA. CONCLUSIONS AND RELEVANCE: PRCA and NRIMHA are uncommon causes of anaemia in predominantly young cats. The prognosis is reasonable, with a mortality rate of 27%, and it can take at least 6 weeks before remission is observed. Following clinical remission, gradual withdrawal of immunosuppressive treatments should be attempted, with close monitoring for relapse; some cats may require long-term treatment. This study is the first to report the use of chlorambucil as an adjunctive immunosuppressant in these cases. Outcome did not differ for PRCA and NRIMHA.
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