Evidence map›Paper›PMID 26116042›Full record

ArticleJournal of biomechanics2015

Men and women have similarly shaped carpometacarpal joint bones.

M T Y Schneider, J Zhang, J J Crisco, A P C Weiss, A L Ladd, P Nielsen, T Besier

Abstract readComparative Study
In one paragraph

Article in Journal of biomechanics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 54 citations in OpenAlex.

  1. Shape predicts osteoarthritis progression in the first carpometacarpal joint.Frontiers in bioengineering and biotechnology · 2026
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  14. Osteophyte volume calculation using dissimilarity-excluding Procrustes registration of archived bone models from healthy volunteers.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
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  16. Observational
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  20. The Teleology of the Thumb: On Purpose and Design.The Journal of hand surgery · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

M T Y SchneiderAuckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand. Electronic address: msch153@aucklanduni.ac.nz.
J ZhangAuckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.
J J CriscoDepartment of Orthopedics, Warren Alpert Medical School of Brown University, Rhode Island Hospital, RI, USA.
A P C WeissDepartment of Orthopedics, Warren Alpert Medical School of Brown University, Rhode Island Hospital, RI, USA.
A L LaddDepartment of Orthopedic Surgery, Stanford, Stanford University, CA, USA.
P NielsenAuckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand; Department of Engineering Science, The University of Auckland, Auckland, New Zealand.
T BesierAuckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand; Department of Engineering Science, The University of Auckland, Auckland, New Zealand.
University of Auckland · NZAuckland Institute of Studies · NZAuckland University of Technology · NZBrown University · USRhode Island Hospital · USStanford University · US

Funding

Thumb CMC Biomechanics and Early OA ProgressionR01AR059185 · NIAMS · RHODE ISLAND HOSPITAL · PI CRISCO, JOSEPH J · 2011 to 2020
$6.4M
NIAMS NIH HHS AR059185NIAMS NIH HHS R01 AR059185
6 · The paper itself

Abstract

Characterizing the morphology of the carpometacarpal (CMC) joint bones and how they vary across the population is important for understanding the functional anatomy and pathology of the thumb. The purpose of this paper was to develop a statistical shape model of the trapezium and first metacarpal bones to characterize the size and shape of the whole bones across a cohort of 50. We used this shape model to investigate the effects of sex and age on the size and shape of the CMC joint bones and the articulating surface area of the CMC joint. We hypothesized that women have similar shape trapezium and first metacarpal bones compared to men, following scaling for overall size. We also hypothesized that age would be a significant predictor variable for CMC joint bone changes. CT image data and segmented point clouds of 50 CMC bones from healthy adult men and women were obtained from an ongoing study and used to generate two statistical shape models. Statistical analysis of the principal component weights of both models was performed to investigate morphological sex and age differences. We observed sex differences, but were unable to detect any age differences. Between men and women the only difference in morphology of the trapezia and first metacarpal bones was size. These findings confirm our first hypothesis, and suggest that the women have similarly shaped trapezium and first metacarpal bones compared to men. Furthermore, our results reject our second hypothesis, indicating that age is a poor predictor of CMC joint morphology.

Indexed as

AdultCarpometacarpal JointsFemaleHumansMaleMiddle AgedRadiographySex CharacteristicsThumbTrapezium BoneYoung AdultCarpometacarpalCMCSex differencesSSMStatistical shape model

Identifiers

PMID26116042
PMCPMC4592789
OpenAlexW609091612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.