ArticleBioinformatics (Oxford, England)2015
nextflu: real-time tracking of seasonal influenza virus evolution in humans.
Article in Bioinformatics (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed.
- Nextstrain automates real-time phylogenetic analysis of open data for endemic and emerging pathogens.Bioinformatics (Oxford, England) · 2026Article
- Evolutionary patterns of pH1N1 and H3N2 in relation to vaccine use.BMC genomics · 2026Article
- Beyond alarmism: what Australia's influenza season really tells us about Italy.Pathogens and global health · 2026Article
- Influenza vaccine strain selection with an AI-based evolutionary and antigenicity model.Nature medicine · 2025Article
- Exact and efficient phylodynamic simulation from arbitrarily large populations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Dimensionality reduction distills complex evolutionary relationships in seasonal influenza and SARS-CoV-2.bioRxiv : the preprint server for biology · 2024Article
- Early detection of highly transmissible viral variants using phylogenomics.Science advances · 2024Article
- Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin.Cell host & microbe · 2024Article
- Article
- Within-host influenza viral diversity in the pediatric population as a function of age, vaccine, and health status.Virus evolution · 2024Article
- Dimensionality reduction distills complex evolutionary relationships in seasonal influenza and SARS-CoV-2.Virus evolution · 2024Article
- Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin.bioRxiv : the preprint server for biology · 2023Article
- An atlas of continuous adaptive evolution in endemic human viruses.Cell host & microbe · 2023Article
- Phylogenies increase power to detect highly transmissible viral genome variants.medRxiv : the preprint server for health sciences · 2023Article
- Early warning of emerging infectious diseases based on multimodal data.Biosafety and health · 2023Review
- [2021-2022 Influenza and Respiratory Viruses Laboratory Surveillance Report in the Republic of Korea].Jugan geon-gang gwa jilbyeong · 2023Article
- Article
- Tracking the emergence of antigenic variants in influenza A virus epidemics in Brazil.Virus evolution · 2023Article
- Joint visualization of seasonal influenza serology and phylogeny to inform vaccine composition.Frontiers in bioinformatics · 2023Article
- Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammals.Virus evolution · 2023Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
unlabelledSeasonal influenza viruses evolve rapidly, allowing them to evade immunity in their human hosts and reinfect previously infected individuals. Similarly, vaccines against seasonal influenza need to be updated frequently to protect against an evolving virus population. We have thus developed a processing pipeline and browser-based visualization that allows convenient exploration and analysis of the most recent influenza virus sequence data. This web-application displays a phylogenetic tree that can be decorated with additional information such as the viral genotype at specific sites, sampling location and derived statistics that have been shown to be predictive of future virus dynamics. In addition, mutation, genotype and clade frequency trajectories are calculated and displayed. AVAILABILITY AND IMPLEMENTATION: Python and Javascript source code is freely available from https://github.com/blab/nextflu, while the web-application is live at http://nextflu.org. CONTACT: tbedford@fredhutch.org.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.