Evidence map›Paper›PMID 26115965›Full record

ArticleJournal of the American Society for Mass Spectrometry2015

A deeper look into Comet--implementation and features.

Jimmy K Eng, Michael R Hoopmann, Tahmina A Jahan, Jarrett D Egertson, William S Noble, Michael J MacCoss

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers.

0numbers the graph read from it
0cells of the map it votes in
153citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

153 citing papers in PubMed.

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  19. An anti-adhesive peptide found in extracellular vesicles fromCell surface (Amsterdam, Netherlands) · 2025
    Article
  20. Pathogenic diversity ofCell surface (Amsterdam, Netherlands) · 2025
    Article

93 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jimmy K EngDepartment of Genome Sciences, University of Washington, Seattle, WA, USA. engj@uw.edu.
Michael R HoopmannInstitute for Systems Biology, Seattle, WA, USA.
Tahmina A JahanDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Jarrett D EgertsonDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
William S NobleDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Michael J MacCossDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.

Funding

TrainingP41GM103533 · NIGMS · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL · 2012 to 2021
$20.7M
Machine learning analysis of tandem mass spectraR01GM096306 · NIGMS · UNIVERSITY OF WASHINGTON · PI NOBLE, WILLIAM STAFFORD · 2011 to 2014
$2.5M
NIGMS NIH HHS P41 GM103533NIGMS NIH HHS P41GM103533NIGMS NIH HHS R01 GM096306NIGMS NIH HHS R01GM096306
6 · The paper itself

Abstract

The Comet database search software was initially released as an open source project in late 2012. Prior to that, Comet existed as the University of Washington's academic version of the SEQUEST database search tool. Despite its availability and widespread use over the years, some details about its implementation have not been previously disseminated or are not well understood. We address a few of these details in depth and highlight new features available in the latest release. Comet is freely available for download at http://comet-ms.sourceforge.net or it can be accessed as a component of a number of larger software projects into which it has been incorporated. Graphical Abstract ᅟ.

Indexed as

Databases, ProteinSoftwareAlgorithmsProteomicsTandem Mass SpectrometryCometDatabase searchMS/MS

Identifiers

PMID26115965
PMCPMC4607604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.