ArticleNanomedicine : nanotechnology, biology, and medicine2015
Movement of magnetic nanoparticles in brain tissue: mechanisms and impact on normal neuronal function.
Article in Nanomedicine : nanotechnology, biology, and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 59 citations in OpenAlex.
- Magnetic Field-Guided Magnetic Nanoparticles as Neurotherapeutics for Neurological Disorders and Glioblastoma.Life (Basel, Switzerland) · 2026Review
- Synthesis of Gd-DTPA Carborane-Containing Compound and Its Immobilization on Iron Oxide Nanoparticles for Potential Application in Neutron Capture Therapy.Pharmaceutics · 2024Article
- Review
- Mathematical Optimisation of Magnetic Nanoparticle Diffusion in the Brain White Matter.International journal of molecular sciences · 2023Article
- Biological Impact of γ-FeBiosensors · 2022Article
- New Acetamidine Cu(II) Schiff base complex supported on magnetic nanoparticles pectin for the synthesis of triazoles using click chemistry.Scientific reports · 2022Article
- Step-by-Step Design of New Theranostic Nanoformulations: Multifunctional Nanovectors for Radio-Chemo-Hyperthermic Therapy under Physical Targeting.Molecules (Basel, Switzerland) · 2021Article
- Article
- Therapeutic Potential of Magnetic Nanoparticle-Based Human Adipose-Derived Stem Cells in a Mouse Model of Parkinson's Disease.International journal of molecular sciences · 2021Article
- A brain glioma gene delivery strategy by angiopep-2 and TAT-modified magnetic lipid-polymer hybrid nanoparticles.RSC advances · 2020Article
- Biodistribution, biocompatibility and targeted accumulation of magnetic nanoporous silica nanoparticles as drug carrier in orthopedics.Journal of nanobiotechnology · 2020Article
- Rotating Magnetic Nanoparticle Clusters as Microdevices for Drug Delivery.International journal of nanomedicine · 2020Article
- Evaluation of Targeted Delivery to the Brain Using Magnetic Immunoliposomes and Magnetic Force.Materials (Basel, Switzerland) · 2019Article
- Traditional Acupuncture Meets Modern Nanotechnology: Opportunities and Perspectives.Evidence-based complementary and alternative medicine : eCAM · 2019Review
- A Novel Magnetic Actuation Scheme to Disaggregate Nanoparticles and Enhance Passage across the Blood-Brain Barrier.Nanomaterials (Basel, Switzerland) · 2017Article
- Magnetic Nanoparticles in the Central Nervous System: Targeting Principles, Applications and Safety Issues.Molecules (Basel, Switzerland) · 2017Review
- Magnetic hyperthermia enhance the treatment efficacy of peri-implant osteomyelitis.BMC infectious diseases · 2017Article
- Magnetic Nanoparticles for Antibiotics Detection.Nanomaterials (Basel, Switzerland) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Magnetic nanoparticles (MNPs) have been used as effective vehicles for targeted delivery of theranostic agents in the brain. The advantage of magnetic targeting lies in the ability to control the concentration and distribution of therapy to a desired target region using external driving magnets. In this study, we investigated the behavior and safety of MNP motion in brain tissue. We found that MNPs move and form nanoparticle chains in the presence of a uniform magnetic field, and that this chaining is influenced by the applied magnetic field intensity and the concentration of MNPs in the tissue. Using electrophysiology recordings, immunohistochemistry and fluorescent imaging we assessed the functional health of neurons and neural circuits and found no adverse effects associated with MNP motion through brain tissue. FROM THE CLINICAL EDITOR: Much research has been done to test the use of nanocarriers for gaining access across the blood brain barrier (BBB). In this respect, magnetic nanoparticles (MNPs) are one of the most studied candidates. Nonetheless, the behavior and safety of MNP once inside brain tissue remains unknown. In this article, the authors thus studied this very important subject.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.