ArticleEnvironmental health perspectives2016
Prenatal Exposure to NO2 and Ultrasound Measures of Fetal Growth in the Spanish INMA Cohort.
Article in Environmental health perspectives, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- The associations of air pollution exposure during pregnancy with fetal growth and anthropometric measurements at birth: a systematic review and meta-analysis.Environmental science and pollution research international · 2019Pooled it
- Prenatal Exposure to Ambient Air Pollution and Fetal Growth Trajectories in Wuhan, China.Environmental health perspectives · 2026Article
- In utero air pollution exposure and pre- and postnatal brain development: a review.Neuroscience applied · 2026Review
- Mapping of Determinants of Urinary Sex Steroid Metabolites During Late Pregnancy: Results from Two Spanish Cohorts.International journal of molecular sciences · 2025Article
- Air Pollution Impact on Pregnancy and Early Childhood Development (APiPED) in India: Protocol for a Cohort Study.JMIR research protocols · 2025Article
- A protocol for estimating health burden posed by early life exposure to ambient fine particulate matter and its heavy metal composition: a mother-child birth (ELitE) cohort from Central India.Frontiers in public health · 2025Article
- Article
- Assessment of exposure to secondhand tobacco smoke in Spain: A scoping review.Tobacco induced diseases · 2024Article
- Traffic-Related Air Pollution and Ultrasound Parameters of Fetal Growth in Eastern Massachusetts.American journal of epidemiology · 2023Article
- Environmental factors affecting pregnancy outcomes.Endocrine · 2023Review
- Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort.Environmental research · 2023Article
- Identifying pre-conception and pre-natal periods in which ambient air pollution exposure affects fetal growth in the predominately Hispanic MADRES cohort.Environmental health : a global access science source · 2022Article
- Impact assessment of particulate pollution on maternal mortality in Nigeria.Scientific reports · 2022Article
- Article
- Maternal exposure to ambient fine particulate matter and fetal growth in Shanghai, China.Environmental health : a global access science source · 2019Article
- Effects of prenatal exposure to ambient air pollutant PM10 on ultrasound-measured fetal growth.International journal of epidemiology · 2018Article
- Prenatal Exposure to Nitrogen Oxides and its Association with Birth Weight in a Cohort of Mexican Newborns from Morelos, Mexico.Annals of global health · 2018Article
- Exposure to Bisphenol A and Phthalates during Pregnancy and Ultrasound Measures of Fetal Growth in the INMA-Sabadell Cohort.Environmental health perspectives · 2016Article
- Effect of Environmental Factors on Low Weight in Non-Premature Births: A Time Series Analysis.PloS one · 2016Article
- Prenatal Exposure to Polybrominated Flame Retardants and Fetal Growth in the INMA Cohort (Spain).Environmental science & technology · 2015Article
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAir pollution exposure during pregnancy has been associated with impaired fetal growth. However, few studies have measured fetal biometry longitudinally, remaining unclear as to whether there are windows of special vulnerability.
objectiveThe aim was to investigate the impact of nitrogen dioxide (NO2) exposure on fetal and neonatal biometry in the Spanish INMA study.
methodsBiparietal diameter (BPD), femur length (FL), abdominal circumference (AC), and estimated fetal weight (EFW) were evaluated for up to 2,478 fetuses in each trimester of pregnancy. Size at 12, 20, and 34 weeks of gestation and growth between these points, as well as anthropometry at birth, were assessed by SD scores derived using cohort-specific growth curves. Temporally adjusted land-use regression was used to estimate exposure to NO2 at home addresses for up to 2,415 fetuses. Associations were investigated by linear regression in each cohort and subsequent meta-analysis.
resultsA 10-μg/m(3) increase in average exposure to NO2 during weeks 0-12 was associated with reduced growth at weeks 0-12 in AC (-2.1%; 95% CI: -3.7, -0.6) and EFW (-1.6%; 95% CI: -3.0, -0.3). The same exposure was inversely associated with reduced growth at weeks 20-34 in BPD (-2.6%; 95% CI: -3.9, -1.2), AC (-1.8%; 95% CI: -3.3, -0.2), and EFW (-2.1%; 95% CI: -3.7, -0.2). A less consistent pattern of association was observed for FL. The negative association of this exposure with BPD and EFW was significantly stronger in smoking versus nonsmoking mothers.
conclusionsMaternal exposure to NO2 in early pregnancy was associated with reduced fetal growth based on ultrasound measures of growth during pregnancy and measures of size at birth.
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