Evidence map›Paper›PMID 26114763›Full record

ArticleSurgical infections2015

Swabbing Surgical Sites Does Not Improve the Detection of Staphylococcus aureus Carriage in High-Risk Surgical Patients.

Jennifer Brown, Chin-Shang Li, Mauro Giordani, Kiarash Shahlaie, Eric O Klineberg, Joanna R Tripet-Diel, Marie S Ihara, Stuart H Cohen

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Surgical infections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jennifer Brown1 Division of Infectious Diseases, Department of Internal Medicine, University of California , Davis Medical Center, Sacramento, California.
Chin-Shang Li2 Division of Biostatistics, Department of Public Health Sciences, School of Medicine, University of California , Davis, Sacramento, California.
Mauro Giordani3 Department of Orthopedic Surgery, University of California , Davis Medical Center, Sacramento, California.
Kiarash Shahlaie4 Department of Neurological Surgery, University of California , Davis Medical Center, Sacramento, California.
Eric O Klineberg3 Department of Orthopedic Surgery, University of California , Davis Medical Center, Sacramento, California.
Joanna R Tripet-Diel1 Division of Infectious Diseases, Department of Internal Medicine, University of California , Davis Medical Center, Sacramento, California.
Marie S Ihara1 Division of Infectious Diseases, Department of Internal Medicine, University of California , Davis Medical Center, Sacramento, California.
Stuart H Cohen1 Division of Infectious Diseases, Department of Internal Medicine, University of California , Davis Medical Center, Sacramento, California.
University of California, Davis · USUniversity of California Davis Medical Center · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR000002 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2012 to 2015
$12.2M
NCATS NIH HHS UL1 TR000002
6 · The paper itself

Abstract

backgroundA major risk factor for the development of surgical site infections is Staphylococcus aureus carriage. Compared with non-carriers, S. aureus carriers have up to a 14-fold greater risk for post-surgical infections. Pre-operative screening for S. aureus carriage is controversial. Yet, targeted screening in high-risk patients or from clinically relevant sites may be beneficial. We aimed to determine whether S. aureus detection in high-risk surgical patients would be increased by culturing surgical sites, in addition to the nares, vs. nares-only culturing.

methodsAdults undergoing pre-operative evaluations in orthopedic and neurosurgical clinics were eligible for participation. For each subject, specimens were collected from the anterior nares and from the proposed surgical site. Samples were inoculated onto methicillin-resistant S. aureus-selective chromogenic agar plates and blood agar plates.

resultsOf 150 subjects, 80 (53.3%) were women and 70 (46.7%) men. The mean age was 61 years and 77/150 (51.3%) had a BMI≥30. Culture results were available for 147/150 subjects. Of the 147 surgical site cultures, 54 (36.7%), 51 (34.7%), and 28 (19.0%) were collected from knee, hip, and lumbar sites, respectively; the remaining 14 (9.5%) were from cervical, thoracic, or infra-clavicular sites. Overall, 35/147 (23.8%) nasal cultures grew S. aureus; 29/147 (19.7%) grew methicillin-susceptible S. aureus (MSSA), and 6/147 (4.1%) grew methicillin-resistant S. aureus (MRSA). Only 2/147 (1.4%) surgical site cultures grew S. aureus; both grew MSSA and MSSA was cultured also from the nasal swabs of these subjects. Using nasal culture+surgical site culture as "true positive," the percentage of additional S. aureus carriers detected by the addition of surgical site screening was zero as compared to nasal screening alone.

conclusionsThe detection of S. aureus carriage in high-risk surgical patients is not improved by swabbing surgical sites in addition to the nares.

Indexed as

AdultAgedAged, 80 and overCarrier StateFemaleHumansMaleMass ScreeningMiddle AgedNosePreoperative CareProspective StudiesRisk AssessmentSkinSpecimen HandlingStaphylococcal Infections

Identifiers

PMID26114763
PMCPMC4593933
OpenAlexW1903461003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.