Evidence map›Paper›PMID 26114697›Full record

ReviewBritish dental journal2015

Biological agents: what they are, how they affect oral health and how they can modulate oral healthcare.

E Georgakopoulou, C Scully

Abstract readReview
PubMed Publisher
In one paragraph

Review in British dental journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Anti-thrombotic agents.British dental journal · 2015
    Article
  5. Increasing collaboration between GPs and dental practitioners.The British journal of general practice : the journal of the Royal College of General Practitioners · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

E GeorgakopoulouDepartment of Histology and Embryology, School of Medicine, University of Athens, Greece.
C Scully1] WHO Collaborating Centre for Oral Health-General Health Co-Director London [2] Royal College of Surgeons of Edinburgh King James IV Professor London [3] UCL Emeritus Professor, London.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological agents - biologics, biologicals or biopharmaceuticals - are any medicinal product manufactured in, or extracted from, a biological source. They are often generated by DNA recombinant biotechnology and several dozen therapeutic monoclonal antibodies (mAbs) are now marketed for a variety of indications, increasingly in the management of inflammatory immune-mediated disorders, transplantation rejection and cancer treatments. Immunomodulatory mAbs are expensive, must be given by injection or infusion and can have adverse effects but are increasingly used and can be highly effective agents. This paper reviews these agents and their increasing relevance to oral science and healthcare.

Indexed as

Dental CareOral HealthAntibodies, MonoclonalBiological FactorsHumansAntibodies, MonoclonalBiological Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.