ArticlePloS one2015
MamA as a Model Protein for Structure-Based Insight into the Evolutionary Origins of Magnetotactic Bacteria.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- The Role of Confinement in Biomineralization.Chemical reviews · 2025Review
- Gas and light: triggers of c-di-GMP-mediated regulation.FEMS microbiology reviews · 2023Review
- Expanding magnetic organelle biogenesis in the domain Bacteria.Microbiome · 2020Article
- Magnetosome Gene Duplication as an Important Driver in the Evolution of Magnetotaxis in themSystems · 2019Article
- Four-stranded mini microtubules formed byProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Origin of microbial biomineralization and magnetotaxis during the Archean.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Article
- A protein-protein interaction in magnetosomes: TPR protein MamA interacts with an Mms6 protein.Biochemistry and biophysics reports · 2016Article
- Living Life on a Magnet.PLoS biology · 2016Article
- From invagination to navigation: The story of magnetosome-associated proteins in magnetotactic bacteria.Protein science : a publication of the Protein Society · 2016Review
- Correction: MamA as a Model Protein for Structure-Based Insight into the Evolutionary Origins of Magnetotactic Bacteria.PloS one · 2015Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MamA is a highly conserved protein found in magnetotactic bacteria (MTB), a diverse group of prokaryotes capable of navigating according to magnetic fields - an ability known as magnetotaxis. Questions surround the acquisition of this magnetic navigation ability; namely, whether it arose through horizontal or vertical gene transfer. Though its exact function is unknown, MamA surrounds the magnetosome, the magnetic organelle embedding a biomineralised nanoparticle and responsible for magnetotaxis. Several structures for MamA from a variety of species have been determined and show a high degree of structural similarity. By determining the structure of MamA from Desulfovibrio magneticus RS-1 using X-ray crystallography, we have opened up the structure-sequence landscape. As such, this allows us to perform structural- and phylogenetic-based analyses using a variety of previously determined MamA from a diverse range of MTB species across various phylogenetic groups. We found that MamA has remained remarkably constant throughout evolution with minimal change between different taxa despite sequence variations. These findings, coupled with the generation of phylogenetic trees using both amino acid sequences and 16S rRNA, indicate that magnetotaxis likely did not spread via horizontal gene transfer and instead has a significantly earlier, primordial origin.
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Registered trials
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