Evidence map›Paper›PMID 26114109›Full record

ArticleBioMed research international2015

A Novel Restraining Device for Small Animal Imaging Exams: Validation in Rabbits.

Carlos Henrique Barbosa, Antonio Carlos Carvalho, Sérgio de Souza, Fernanda Machado, Fábio Guedes, André Monteiro, Alberto Schanaider

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carlos Henrique BarbosaCenter of Experimental Surgery, Department of Surgery, School of Medicine, Federal University of Rio de Janeiro, 21941-913 Rio de Janeiro, RJ, Brazil ; Orofacial Pain and Masticatory Dysfunction Clinic, Department of Dental Clinic, School of Dentistry, Federal University of Rio de Janeiro, 21941-902 Rio de Janeiro, RJ, Brazil.
Antonio Carlos CarvalhoDepartment of Radiology, School of Medicine, Federal University of Rio de Janeiro, 21941-913 Rio de Janeiro, RJ, Brazil.
Sérgio de SouzaDepartment of Radiology, School of Medicine, Federal University of Rio de Janeiro, 21941-913 Rio de Janeiro, RJ, Brazil.
Fernanda MachadoOrofacial Pain and Masticatory Dysfunction Clinic, Department of Dental Clinic, School of Dentistry, Federal University of Rio de Janeiro, 21941-902 Rio de Janeiro, RJ, Brazil.
Fábio GuedesDepartment of Pathology and Oral Diagnosis, Dental School, Federal University of Rio de Janeiro, 21941-902 Rio de Janeiro, RJ, Brazil.
André MonteiroOrofacial Pain and Masticatory Dysfunction Clinic, Department of Dental Clinic, School of Dentistry, Federal University of Rio de Janeiro, 21941-902 Rio de Janeiro, RJ, Brazil.
Alberto SchanaiderCenter of Experimental Surgery, Department of Surgery, School of Medicine, Federal University of Rio de Janeiro, 21941-913 Rio de Janeiro, RJ, Brazil.
Universidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop, validate, and patent a Restraining Device for Small Animal Imaging Exams (RDSAIE) that allows exams to be comfortably conducted without risks to animals and professionals.

methodsA RDSAIE with a mobile cover and shelf was built with transparent acrylic material. A total of six anesthetized rabbits were used to perform the following imaging exams of the skull: Cone Beam Computed Tomography, Magnetic Resonance Imaging, and Scintigraphy.

resultsThe device showed great functionality and full visibility of the animal behavior, which remained fully stabilized and immobilized in either the horizontal or vertical position without the need for a person to remain in the test room to assist them. The procedures were performed without difficulty, and images of good resolution and without artifacts were obtained.

conclusionThe RDSAIE is comfortable, safe, efficient, and ergonomic. It allows the easy placement of animals in different body positions, including the vertical, the maintenance of postural stability, and full visibility. It may be constructed for animals heavier than 4 kg and it is adaptable for translational studies in anima nobile.

Indexed as

Phantoms, ImagingAnimalsCone-Beam Computed TomographyImage Processing, Computer-AssistedRabbitsSkull

Identifiers

PMID26114109
PMCPMC4465649
OpenAlexW1559734777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.