ArticleBiomedical optics express2015
In vivo quantitation of injected circulating tumor cells from great saphenous vein based on video-rate confocal microscopy.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 38 citations in OpenAlex.
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- 3D cellular visualization of intact mouse tooth using optical clearing without decalcification.International journal of oral science · 2019Article
- Post-debulking circulating tumor cell as a poor prognostic marker in advanced stage ovarian cancer: A prospective observational study.Medicine · 2019Observational
- Neutrophils disturb pulmonary microcirculation in sepsis-induced acute lung injury.The European respiratory journal · 2019Article
- Real-time in vivo imaging of subpopulations of circulating tumor cells using antibody conjugated quantum dots.Journal of nanobiotechnology · 2019Article
- Quinic Acid-Conjugated Nanoparticles Enhance Drug Delivery to Solid Tumors via Interactions with Endothelial Selectins.Small (Weinheim an der Bergstrasse, Germany) · 2018Article
- Intravital imaging of a pulmonary endothelial surface layer in a murine sepsis model.Biomedical optics express · 2018Article
- Clinical significance of circulating tumor cells from lung cancer patients using microfluidic chip.Clinical and experimental medicine · 2018Article
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- Label-free high-throughput detection and quantification of circulating melanoma tumor cell clusters by linear-array-based photoacoustic tomography.Journal of biomedical optics · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of circulating tumor cell (CTC) in the peripheral blood of cancer patients can be a valuable biomarker for cancer diagnosis and treatment monitoring. In this study, we implemented a custom-design video-rate confocal microscopy system in capable of direct visualization of fast flowing CTC at great saphenous vein (GSV) of a live animal model in vivo. Continuous acquisition of video-rate images at GSV revealed the highly dynamic time-dependent changes in the number of intravenously injected circulating tumor cells. By extracting a calibration factor through the hemocytometric analysis of intravenously injected long-circulating red blood cells, we established a novel quantitation method for CTC in whole body blood in vivo.
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