Evidence map›Paper›PMID 26114021›Full record

ArticleBiomedical optics express2015

Dual shear wave induced laser speckle contrast signal and the improvement in shear wave speed measurement.

Sinan Li, Yi Cheng, Robert J Eckersley, Daniel S Elson, Meng-Xing Tang

Abstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sinan LiDepartment of Bioengineering, Imperial College London, London, SW7 2AZ, UK.
Yi ChengDepartment of Bioengineering, Imperial College London, London, SW7 2AZ, UK.
Robert J EckersleyDepartment of Biomedical Engineering, King's College London, London, SE1 7EH, UK.
Daniel S ElsonDepartment of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK ; daniel.elson@imperial.ac.uk.
Meng-Xing TangDepartment of Bioengineering, Imperial College London, London, SW7 2AZ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shear wave speed is quantitatively related to tissue viscoelasticity. Previously we reported shear wave tracking at centimetre depths in a turbid optical medium using laser speckle contrast detection. Shear wave progression modulates displacement of optical scatterers and therefore modulates photon phase and changes the laser speckle patterns. Time-resolved charge-coupled device (CCD)-based speckle contrast analysis was used to track shear waves and measure the time-of-flight of shear waves for speed measurement. In this manuscript, we report a new observation of the laser speckle contrast difference signal for dual shear waves. A modulation of CCD speckle contrast difference was observed and simulation reproduces the modulation pattern, suggesting its origin. Both experimental and simulation results show that the dual shear wave approach generates an improved definition of temporal features in the time-of-flight optical signal and an improved signal to noise ratio with a standard deviation less than 50% that of individual shear waves. Results also show that dual shear waves can correct the bias of shear wave speed measurement caused by shear wave reflections from elastic boundaries.

Indexed as

(110.0113) Imaging through turbid media(170.1065) Acousto-optics

Identifiers

PMID26114021
PMCPMC4473736

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.