ArticleJournal of the International Society of Sports Nutrition2015
Rhabdomyolysis and exercise-associated hyponatremia in ultra-bikers and ultra-runners.
Article in Journal of the International Society of Sports Nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 52 citations in OpenAlex.
- Increased risk of acute kidney injury in the first part of an ultra-trail-Implications for abandonment.Physiological reports · 2024Article
- Ultra-Cycling- Past, Present, Future: A Narrative Review.Sports medicine - open · 2024Review
- Characteristics and treatments of patients with significantly elevated creatine kinase levels induced by seizures: Case report and literature review.Clinical case reports · 2023Article
- Ultra-Endurance Participation and Acute Kidney Injury: A Narrative Review.International journal of environmental research and public health · 2022Review
- 768-km Multi-Stage Ultra-Trail Case Study-Muscle Damage, Biochemical Alterations and Strength Loss on Lower Limbs.International journal of environmental research and public health · 2022Article
- Extreme Ultra-Trail Race Induces Muscular Damage, Risk for Acute Kidney Injury and Hyponatremia: A Case Report.International journal of environmental research and public health · 2021Article
- Relationship between Skin Temperature Variation and Muscle Damage Markers after a Marathon Performed in a Hot Environmental Condition.Life (Basel, Switzerland) · 2021Article
- Wet Bulb Globe Temperature and Recorded Occupational Injury Rates among Sugarcane Harvesters in Southwest Guatemala.International journal of environmental research and public health · 2020Article
- Physiological Responses and Nutritional Intake during a 7-Day Treadmill Running World Record.International journal of environmental research and public health · 2020Article
- Nutrition-Related Adverse Outcomes in Endurance Sports Competitions: A Review of Incidence and Practical Recommendations.International journal of environmental research and public health · 2020Review
- Effect of mountain ultramarathon distance competition on biochemical variables, respiratory and lower-limb fatigue.PloS one · 2020Article
- Life-threatening heat-related illness with severe hyponatremia in an aluminum smelter worker.American journal of industrial medicine · 2019Article
- Exercise-Associated Hyponatremia in Endurance and Ultra-Endurance Performance-Aspects of Sex, Race Location, Ambient Temperature, Sports Discipline, and Length of Performance: A Narrative Review.Medicina (Kaunas, Lithuania) · 2019Review
- Heat Strain, External Workload, and Chronic Kidney Disease in Tropical Settings: Are Endurance Athletes Exposed?Frontiers in physiology · 2019Article
- Incidence of Hyponatremia During a Continuous 246-km Ultramarathon Running Race.Frontiers in nutrition · 2019Article
- Sport Readaptation: Where Do We Draw the Lines Between Professionals?Frontiers in sports and active living · 2019Article
- Body Composition Changes During a 24-h Winter Mountain Running Race Under Extremely Cold Conditions.Frontiers in physiology · 2019Article
- Sugarcane cutting work, risks, and health effects: a literature review.Revista de saude publica · 2018Review
- National Athletic Trainers' Association Position Statement: Fluid Replacement for the Physically Active.Journal of athletic training · 2017Article
- Reported Hydration Beliefs and Behaviors without Effect on Plasma Sodium in Endurance Athletes.Frontiers in physiology · 2017Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExercise-associated hyponatremia (EAH), rhabdomyolysis and renal failure appear to be a unique problem in ultra-endurance racers.
methodsWe investigated the combined occurrence of EAH and rhabdomyolysis in seven different ultra-endurance races and disciplines (i.e. multi-stage mountain biking, 24-h mountain biking, 24-h ultra-running and 100-km ultra-running).
resultsTwo (15.4%) ultra-runners (man and woman) from hyponatremic ultra-athletes (n = 13) and four (4%) ultra-runners (four men) from the normonatremic group (n = 100) showed rhabdomyolysis following elevated blood creatine kinase (CK) levels > 10,000 U/L without the development of renal failure and the necessity of a medical treatment. Post-race creatine kinase, plasma and urine creatinine significantly increased, while plasma [Na(+)] and creatine clearance decreased in hyponatremic and normonatremic athletes, respectively. The percentage increase of CK was higher in the hyponatremic compared to the normonatremic group (P < 0.05). Post-race CK levels were higher in ultra-runners compared to mountain bikers (P < 0.01), in faster normonatremic (P < 0.05) and older and more experienced hyponatremic ultra-athletes (P < 0.05). In all finishers, pre-race plasma [K(+)] was related to post-race CK (P < 0.05).
conclusionsHyponatremic ultra-athletes tended to develop exercise-induced rhabdomyolysis more frequently than normonatremic ultra-athletes. Ultra-runners tended to develop rhabdomyolysis more frequently than mountain bikers. We found no association between post-race plasma [Na(+)] and CK concentration in both hypo- and normonatremic ultra-athletes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.